mismatch

By Targets:	Apoptosis (2) Autophagy (2) DNA Alkylator/Crosslinker (2) DNA/RNA Synthesis (1) Endogenous Metabolite (1) Nucleoside Antimetabolite/Analog (2)
By Research Areas:	Cancer (5)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-116887

N6-Methyladenine	Endogenous Metabolite Nucleoside Antimetabolite/Analog DNA/RNA Synthesis	Cancer
N6-Methyladenine is a modified purine that is widely present in prokaryotes. In prokaryotes, N6-Methyladenine plays an important role in distinguishing host DNA from exogenous DNA and controls many biological functions, such as DNA replication, transcription, mismatch repair, and chromosome replication .

HY-148503

5'-ODMT cEt N-Bz A Phosphoramidite (Amidite)	Nucleoside Antimetabolite/Analog	Cancer
5'-ODMT cEt N-Bz A Phosphoramidite Amidite is a locked nucleic acid (LNA) analogue. 5'-ODMT cEt N-Bz A Phosphoramidite Amidite possesses hybridization and mismatch discrimination attributes similar to those of LNA and shows resistance to exonuclease digestion .

HY-17364

Temozolomide 105+ Cited Publications NSC 362856; CCRG 81045; TMZ	DNA Alkylator/Crosslinker Autophagy Apoptosis	Cancer
Temozolomide (NSC 362856) is an oral active DNA alkylating agent that crosses the blood-brain barrier. Temozolomide is also a proautophagic and proapoptotic agent. Temozolomide is effective against tumor cells that are characterized by low levels of O6-alkylguanine DNA alkyltransferase (OGAT) and a functional mismatch repair system. Temozolomide has antitumor and antiangiogenic effects .

HY-17364S

Temozolomide-d3	DNA Alkylator/Crosslinker Autophagy Apoptosis	Cancer
Temozolomide-d₃ is the deuterium labeled Temozolomide. Temozolomide (NSC 362856) is an oral active DNA alkylating agent that crosses the blood-brain barrier. Temozolomide is also a proautophagic and proapoptotic agent. Temozolomide is effective against tumor cells that are characterized by low levels of O6-alkylguanine DNA alkyltransferase (OGAT) and a functional mismatch repair system. Temozolomide has antitumor and antiangiogenic effects[1][2].

HY-153805

Z-NCTS

Others Cancer

Z-NCTS is an RNA mismatch binding molecule that recognizes the 5’-r(XGG)-3’/5’-r(XGG)-3’ sequence (X=U or A) and acts as a molecular glue for RNA .

Z-NCTS	Others	Cancer
Z-NCTS is an RNA mismatch binding molecule that recognizes the 5’-r(XGG)-3’/5’-r(XGG)-3’ sequence (X=U or A) and acts as a molecular glue for RNA .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-116887

N6-Methyladenine	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite Nucleoside Antimetabolite/Analog DNA/RNA Synthesis
N6-Methyladenine is a modified purine that is widely present in prokaryotes. In prokaryotes, N6-Methyladenine plays an important role in distinguishing host DNA from exogenous DNA and controls many biological functions, such as DNA replication, transcription, mismatch repair, and chromosome replication .

Cat. No.	Compare	Product Name	Species	Source

HY-P73803

	MSH2 Protein, Human (sf9, His-GST) DNA mismatch repair protein Msh2; hMSH2; MSH2	Human	Sf9 insect cells
	MSH2 protein is a key component of the DNA mismatch repair system, which can recognize and bind DNA mismatches to initiate repair. MSH2 forms heterodimers MutS α and MutS β that target various mismatches. MSH2 Protein, Human (sf9, His-GST) is the recombinant human-derived MSH2 protein, expressed by Sf9 insect cells , with C-His, N-GST labeled tag. The total length of MSH2 Protein, Human (sf9, His-GST) is 934 a.a., with molecular weight of ~132.6 kDa.


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name	Chemical Structure

HY-17364S

Temozolomide-d3
Temozolomide-d₃ is the deuterium labeled Temozolomide. Temozolomide (NSC 362856) is an oral active DNA alkylating agent that crosses the blood-brain barrier. Temozolomide is also a proautophagic and proapoptotic agent. Temozolomide is effective against tumor cells that are characterized by low levels of O6-alkylguanine DNA alkyltransferase (OGAT) and a functional mismatch repair system. Temozolomide has antitumor and antiangiogenic effects[1][2].

Temozolomide-d3

Temozolomide-d₃ is the deuterium labeled Temozolomide. Temozolomide (NSC 362856) is an oral active DNA alkylating agent that crosses the blood-brain barrier. Temozolomide is also a proautophagic and proapoptotic agent. Temozolomide is effective against tumor cells that are characterized by low levels of O6-alkylguanine DNA alkyltransferase (OGAT) and a functional mismatch repair system. Temozolomide has antitumor and antiangiogenic effects[1][2].

Cat. No.	Product Name	Application	Reactivity

HY-P80753

MLH1 Antibody (YA703) MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1	WB, ICC/IF	Human, Monkey
MLH1 Antibody (YA703) is a non-conjugated and Mouse origined monoclonal antibody about 85 kDa, targeting to MLH1 (4C1). It can be used for WB,ICC/IF assays with tag free, in the background of Human, Monkey.

HY-P82027

PMS2 Antibody (YA1772)

DNA mismatch repair gene; DNA mismatch repair protein PMS2; HNPCC4; PMS1 protein homolog 2
WB, IP Human

HY-P82011

MSH6 Antibody (YA1756) MSH6; GTBP; DNA mismatch repair protein Msh6; hMSH6; G/T mismatch-binding protein; GTBP; GTMBP; MutS-alpha 160 kDa subunit; p160	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat

HY-P82029

MSH2 Antibody (YA1774)

DNA mismatch repair protein Msh2; MutS protein homolog 2
WB Human, Rat

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inhibitors & Agonists

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies