MLH1 Antibody (YA703)

Cat. No.: HY-P80753: FAQs
Data Sheet SDS COA User Guide for Antibodies

MLH1 Antibody (YA703) is a non-conjugated and Mouse origined monoclonal antibody about 85 kDa, targeting to MLH1 (4C1). It can be used for WB,ICC/IF assays with tag free, in the background of Human, Monkey.

For research use only. We do not sell to patients.

Size	Price	Stock	Quantity
10 μL	$100	In-stock	Estimated Time of Arrival: December 31
50 μL	$270	In-stock	Estimated Time of Arrival: December 31
100 μL	$430	In-stock	Estimated Time of Arrival: December 31
250 μL		Get quote

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Biological Activity
Technical Parameters
Properties
Documentation

Description	MLH1 Antibody (YA703) is a non-conjugated and Mouse origined monoclonal antibody about 85 kDa, targeting to MLH1 (4C1). It can be used for WB,ICC/IF assays with tag free, in the background of Human, Monkey.
Background	MLH1 (4C1): The protein encoded by this gene can heterodimerize with mismatch repair endonuclease PMS2 to form MutL alpha, part of the DNA mismatch repair system. When MutL alpha is bound by MutS beta and some accessory proteins, the PMS2 subunit of MutL alpha introduces a single-strand break near DNA mismatches, providing an entry point for exonuclease degradation. The encoded protein is also involved in DNA damage signaling and can heterodimerize with DNA mismatch repair protein MLH3 to form MutL gamma, which is involved in meiosis. This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). [provided by RefSeq, Aug 2017]
Tag	Free
Gene ID	4292
Synonyms	MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1
Molecular Weight	Predicted band size: 85 kDa
Purity	affinity purified
Conjugation	Non-conjugated
Research Field	Epigenetics and Nuclear Signaling
Product Categories	Primary Antibody; Mouse Monoclonal Antibody
Host	Mouse
Reactivity	Human, Monkey
SwissProt ID	P40692
Dilution Ratio	WB: 1:500-1:1,000 ;IF: 1:50-1:200
Application	WB, ICC/IF
Appearance	Liquid
Formulation	Supplied in 1*PBS (pH 7.3), 50% glycerol and 0.5% BSA. Preservative: 0.02% sodium azide.
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG1
Immunogen	Synthetic peptide corresponding to MLH1.AA range:381-483.
Documentation	Select Batch: Data Sheet (234 KB) SDS (251 KB) COA (205 KB) User Guide for Antibodies (1077 KB)

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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MLH1 Antibody (YA703)

Biological Activity

Technical Parameters

Properties

Documentation

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