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Cat. No.: HY-153805

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Z-NCTS

Z-NCTS is an RNA mismatch binding molecule that recognizes the 5’-r(XGG)-3’/5’-r(XGG)-3’ sequence (X=U or A) and acts as a molecular glue for RNA.

For research use only. We do not sell to patients.

CAS No.: 1373391-77-5
Formula: C₆₈H₇₀N₁₄O₈
Molecular Weight:1211.37

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Z-NCTS Chemical Structure

CAS No.: 1373391-77-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Z-NCTS is an RNA mismatch binding molecule that recognizes the 5’-r(XGG)-3’/5’-r(XGG)-3’ sequence (X=U or A) and acts as a molecular glue for RNA^[1].

Chemical Information

CAS No. 1373391-77-5
Molecular Weight 1211.37
Formula C₆₈H₇₀N₁₄O₈
SMILES

CC1=NC2=C(C=C1)C=CC(NC(OCCCN(CCCOC(NC3=NC4=C(C=CC(C)=N4)C=C3)=O)CC(C=C5)=CC=C5/C=C\C(C=C6)=CC=C6CN(CCCOC(NC7=NC8=C(C=CC(C)=N8)C=C7)=O)CCCOC(NC9=NC%10=C(C=CC(C)=N%10)C=C9)=O)=O)=N2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Chikara Dohno, et al. Molecular Glue for RNA: Regulating RNA Structure and Function through Synthetic RNA Binding Molecules. Chembiochem. 2019 Dec 2;20(23):2903-2910. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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