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murine peritoneal neutrophils

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By Targets:	Adrenergic Receptor (1) Interleukin Related (1) Reactive Oxygen Species (ROS) (1)
By Research Areas:	Inflammation/Immunology (2)

Inhibitors & Agonists

Biochemical Assay Reagents

Inhibitory Antibodies

Targets Recommended: BMI1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-NP143

Nerve Growth Factor 2.5S,murine submaxillary gland	Reactive Oxygen Species (ROS) Adrenergic Receptor	Inflammation/Immunology
Nerve Growth Factor 2.5S,murine submaxillary gland is a neurotrophic polypeptide and protein growth factor isolated from murine submaxillary glands. Nerve Growth Factor 2.5S,murine submaxillary gland increases the survival rate, phagocytic capacity and superoxide anion production level of mouse cells. Nerve Growth Factor 2.5S,murine submaxillary gland acts through cell membrane surface receptors to mediate the differentiation and maintenance of adrenergic neurons in the sympathetic nervous system. Nerve Growth Factor 2.5S,murine submaxillary gland loses its activity and undergoes dimer dissociation due to oxidation; it remains active after modification of specific tryptophan residues, while its tyrosine residues are not essential for activity. Nerve Growth Factor 2.5S,murine submaxillary gland may play a role in the inflammatory process .

HY-P992153

Serrumab	Interleukin Related	Inflammation/Immunology
Serrumab is a human monoclonal antibody that counteracts the biochemical and immunological effects of Tityus serrulatus venom. Serrumab inhibits the TsV-induced increase in the production of IL-6, TNFα and IL-10. Serrumab also prevents TsV-induced elevations in plasma urea, creatinine, aspartate transaminase and glucose levels, as well as the TsV-induced increase in neutrophil recruitment. Serrumab can be used in research related to envenoming by the Brazilian yellow scorpion .

Cat. No.	Product Name	Type

HY-NP143

Nerve Growth Factor 2.5S,murine submaxillary gland	Biochemical Assay Reagents
Nerve Growth Factor 2.5S,murine submaxillary gland is a neurotrophic polypeptide and protein growth factor isolated from murine submaxillary glands. Nerve Growth Factor 2.5S,murine submaxillary gland increases the survival rate, phagocytic capacity and superoxide anion production level of mouse cells. Nerve Growth Factor 2.5S,murine submaxillary gland acts through cell membrane surface receptors to mediate the differentiation and maintenance of adrenergic neurons in the sympathetic nervous system. Nerve Growth Factor 2.5S,murine submaxillary gland loses its activity and undergoes dimer dissociation due to oxidation; it remains active after modification of specific tryptophan residues, while its tyrosine residues are not essential for activity. Nerve Growth Factor 2.5S,murine submaxillary gland may play a role in the inflammatory process .

Nerve Growth Factor 2.5S,murine submaxillary gland

Biochemical Assay Reagents

Nerve Growth Factor 2.5S,murine submaxillary gland is a neurotrophic polypeptide and protein growth factor isolated from murine submaxillary glands. Nerve Growth Factor 2.5S,murine submaxillary gland increases the survival rate, phagocytic capacity and superoxide anion production level of mouse cells. Nerve Growth Factor 2.5S,murine submaxillary gland acts through cell membrane surface receptors to mediate the differentiation and maintenance of adrenergic neurons in the sympathetic nervous system. Nerve Growth Factor 2.5S,murine submaxillary gland loses its activity and undergoes dimer dissociation due to oxidation; it remains active after modification of specific tryptophan residues, while its tyrosine residues are not essential for activity. Nerve Growth Factor 2.5S,murine submaxillary gland may play a role in the inflammatory process .

Cat. No.	Product Name	Target	Research Area	Image

HY-P992153

Serrumab	Interleukin Related	Inflammation/Immunology
Serrumab is a human monoclonal antibody that counteracts the biochemical and immunological effects of Tityus serrulatus venom. Serrumab inhibits the TsV-induced increase in the production of IL-6, TNFα and IL-10. Serrumab also prevents TsV-induced elevations in plasma urea, creatinine, aspartate transaminase and glucose levels, as well as the TsV-induced increase in neutrophil recruitment. Serrumab can be used in research related to envenoming by the Brazilian yellow scorpion .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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