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muscarinic spare receptors

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Nom du produit Target Áreas de investigación Chemical Structure
  • HY-186083
    Propylbenzilylcholine mustard

    		mAChR Cardiovascular Disease
    Propylbenzilylcholine mustard (PrBCM) is an irreversible, covalently binding selective antagonist targeting rat cardiac muscarinic receptors, with a preference for muscarinic receptor subtypes that show low affinity for agonists. Propylbenzilylcholine mustard inactivates such receptors in a dose- and time-dependent manner in vitro, and its receptor selectivity remains stable across different ionic strengths and in GTP-containing buffer systems. Propylbenzilylcholine mustard can be applied to basic pharmacological studies on the structure and function of muscarinic receptors, especially focusing on the heterogeneity of cardiac muscarinic receptors and related cardiovascular pharmacological research .
    Propylbenzilylcholine mustard

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