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Results for "

pyridazine derivatives

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

1

Biochemical Assay Reagents

Targets Recommended:
Cat. No. 상품명 Target 연구분야 Chemical Structure
  • HY-Y0141
    3-Amino-6-chloropyridazine

    		Drug Intermediate Others
    3-Amino-6-chloropyridazine is a nitrogen-containing heterocyclic organic compound belonging to the pyridazine derivatives. 3-Amino-6-chloropyridazine has the basicity of amino groups and the nucleophilic substitution activity of chlorine atoms. 3-Amino-6-chloropyridazine can serve as an important intermediate for synthesizing some active compounds .
    3-Amino-6-chloropyridazine
  • HY-150753
    RS6212
    1 Publications Verification

    		 Oxidative Phosphorylation Lactate Dehydrogenase Cancer
    RS6212 is a specific LDH (lactate dehydrogenase) inhibitor with an IC50 value of 12.03 μM . RS6212 inhibits tumor growth and exhibits potent anticancer activity in multiple cancer cell lines .
    RS6212
  • HY-176439
    AChE-IN-88

    		Amyloid-β Cholinesterase (ChE) Neurological Disease
    AChE-IN-88 (Compound 26) is a novel pyridazine derivative. AChE-IN-88 is an orally active multi-target ligand for Alzheimer's disease (AD) that inhibits both acetylcholinesterase (AChE) and amyloid β protein (Aβ) aggregation (pIC50: 7.16) .
    AChE-IN-88
  • HY-106885
    F 2692

    		Drug Derivative Neurological Disease
    F 2692 is an orally effective derivative of pyridazine. F 2692 has significant anti anxiety effects. F 2692 also has activities such as anticonvulsant, sedative, and muscle relaxant. F 2692 can be used for research on neurological disorders such as anxiety disorders .
    F 2692
  • HY-155648
    Tuberculosis inhibitor 6

    		Bacterial Infection
    Tuberculosis inhibitor 6 (compound 2c) is a 3-methoxy-2-phenylimidazo[1,2-b]pyridazine derivative that shows highly active against Mycobacterium tuberculosis (MIC90 of ≤1.66 μM) and Mycobacterium marinum (MIC90 of 2.65 μM) .
    Tuberculosis inhibitor 6
  • HY-155649
    Tuberculosis inhibitor 7

    		Bacterial Infection
    Tuberculosis inhibitor 7 (compound 2d) is a 3-methoxy-2-phenylimidazo[1,2-b]pyridazine derivative that shows highly active against Mycobacterium tuberculosis (MIC90 of 0.63 μM) and Mycobacterium marinum (MIC90 of 0.63 μM) .
    Tuberculosis inhibitor 7
  • HY-155651
    Tuberculosis inhibitor 9

    		Bacterial Infection
    Tuberculosis inhibitor 9 (compound 3d) is a 3-methoxy-2-phenylimidazo[1,2-b]pyridazine derivative that shows highly active against Mycobacterium tuberculosis (MIC90 of 0.64 μM) and Mycobacterium marinum (MIC90 of 0.64 μM) .
    Tuberculosis inhibitor 9
  • HY-155650
    Tuberculosis inhibitor 8

    		Bacterial Infection
    Tuberculosis inhibitor 8 (compound 3b) is a 3-methoxy-2-phenylimidazo[1,2-b]pyridazine derivative that shows highly active against Mycobacterium tuberculosis (MIC90 of 0.69 μM) and Mycobacterium marinum (MIC90 of 0.69 μM) .
    Tuberculosis inhibitor 8
  • HY-161921
    Antifungal agent 108

    		Fungal Infection
    Antifungal agent 108 (compound 14d), an original imidazo[1,2-b]pyridazine derivative, shows potent antifungal activity against Madurella mycetomatis (MM55 strain) with an IC50 of 0.9 μM. Antifungal agent 108 exhibits an IC50 of 14.3 μM on cell viability of NIH-3T3 murine fibroblast .
    Antifungal agent 108
  • HY-160757
    NLRP3 modulator 7

    		NOD-like Receptor (NLR) Interleukin Related Inflammation/Immunology
    NLRP3 modulator 7 (Compound 17B) is a NLRP3 inflammasome regulator. NLRP3 modulator 7 has inhibitory activity against IL-1b, and its IC50 is less than 500 nM .
    NLRP3 modulator 7

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