3-Amino-6-chloropyridazine
Based on 1 Customer Validation
3-Amino-6-chloropyridazine is a nitrogen-containing heterocyclic organic compound belonging to the pyridazine derivatives. 3-Amino-6-chloropyridazine has the basicity of amino groups and the nucleophilic substitution activity of chlorine atoms. 3-Amino-6-chloropyridazine can serve as an important intermediate for synthesizing some active compounds.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 5469-69-2
- Formula: C4H4ClN3
- Molecular Weight:129.55
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
3-Amino-6-chloropyridazine derivatives, such as 3-Sulfanilyl-6-chloropyridazine, exhibit strong bacteriostatic effects against some bacteria (e.g., Escherichia coli, Staphylococcus aureus, etc.)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 5469-69-2
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Appearance Solid
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Molecular Weight 129.55
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Formula C4H4ClN3
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Color Light brown to yellow
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SMILES
NC1=NN=C(Cl)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
In Vitro:
DMSO : 25 mg/mL (192.98 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. HORIE T, et al. Studies on pyridazine derivatives. I. Synthesis and antimicrobial activity of 6-substituted 3-aminopyridazine and its sulfonamido derivatives. Chem Pharm Bull (Tokyo). 1962 Jul;10:580-91. [Content Brief]
[2]. Hu M M, et al. 3-Amino-6-chloropyridazinium chloride. Structure Reports, 2007, 63(11): o4292-o4292.
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 7.7190 mL | 38.5951 mL | 77.1903 mL | 192.9757 mL |
| 5 mM | 1.5438 mL | 7.7190 mL | 15.4381 mL | 38.5951 mL | |
| 10 mM | 0.7719 mL | 3.8595 mL | 7.7190 mL | 19.2976 mL | |
| 15 mM | 0.5146 mL | 2.5730 mL | 5.1460 mL | 12.8650 mL | |
| 20 mM | 0.3860 mL | 1.9298 mL | 3.8595 mL | 9.6488 mL | |
| 25 mM | 0.3088 mL | 1.5438 mL | 3.0876 mL | 7.7190 mL | |
| 30 mM | 0.2573 mL | 1.2865 mL | 2.5730 mL | 6.4325 mL | |
| 40 mM | 0.1930 mL | 0.9649 mL | 1.9298 mL | 4.8244 mL | |
| 50 mM | 0.1544 mL | 0.7719 mL | 1.5438 mL | 3.8595 mL | |
| 60 mM | 0.1287 mL | 0.6433 mL | 1.2865 mL | 3.2163 mL | |
| 80 mM | 0.0965 mL | 0.4824 mL | 0.9649 mL | 2.4122 mL | |
| 100 mM | 0.0772 mL | 0.3860 mL | 0.7719 mL | 1.9298 mL |
3-Amino-6-chloropyridazine Related Classifications
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