3-Chloro-6-methylpyridazine
Based on 1 Customer Validation
3-Chloro-6-methylpyridazine is a substituted pyridazine derivative containing an electron-withdrawing chlorine atom and an electron-donating methyl group. Pyridazine compounds generally possess pharmacological activities such as antibacterial and anti-inflammatory properties. 3-Chloro-6-methylpyridazine can serve as an organic ligand for constructing organic-inorganic hybrid chloroantimonate materials with semiconducting behavior. 3-Chloro-6-methylpyridazine can be used in studies related to optoelectronic devices, photodetectors, and photocatalysis.
For research use only. We do not sell to patients.
- Purity: 98.05%
- CAS No.: 1121-79-5
- Formula: C5H5ClN2
- Molecular Weight:128.56
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
3-Chloro-6-methylpyridazine (molar ratio of 2:1 with antimony trichloride; 4 days) acts as a cationic ligand to form a one-dimensional organic-inorganic hybrid compound with a monoclinic crystal structure[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1121-79-5
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Appearance Solid
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Molecular Weight 128.56
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Formula C5H5ClN2
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Color Light yellow to brown
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SMILES
CC1=NN=C(Cl)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (777.85 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (19.45 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (19.45 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (273 KB)
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SDS (614 KB)
- English - EN (614 KB)
- Français - FR (614 KB)
- Deutsch - DE (614 KB)
- Norwegian - NO (614 KB)
- Español - ES (614 KB)
- Swedish - SV (614 KB)
- Italian - IT (614 KB)
- Korean - KR (614 KB)
- Portuguese - PT (614 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 7.7785 mL | 38.8923 mL | 77.7847 mL | 194.4617 mL |
| 5 mM | 1.5557 mL | 7.7785 mL | 15.5569 mL | 38.8923 mL | |
| 10 mM | 0.7778 mL | 3.8892 mL | 7.7785 mL | 19.4462 mL | |
| 15 mM | 0.5186 mL | 2.5928 mL | 5.1856 mL | 12.9641 mL | |
| 20 mM | 0.3889 mL | 1.9446 mL | 3.8892 mL | 9.7231 mL | |
| 25 mM | 0.3111 mL | 1.5557 mL | 3.1114 mL | 7.7785 mL | |
| 30 mM | 0.2593 mL | 1.2964 mL | 2.5928 mL | 6.4821 mL | |
| 40 mM | 0.1945 mL | 0.9723 mL | 1.9446 mL | 4.8615 mL | |
| 50 mM | 0.1556 mL | 0.7778 mL | 1.5557 mL | 3.8892 mL | |
| 60 mM | 0.1296 mL | 0.6482 mL | 1.2964 mL | 3.2410 mL | |
| 80 mM | 0.0972 mL | 0.4862 mL | 0.9723 mL | 2.4308 mL | |
| 100 mM | 0.0778 mL | 0.3889 mL | 0.7778 mL | 1.9446 mL |
3-Chloro-6-methylpyridazine Related Classifications
HY-W001297 Related Classifications
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- 3-Chloro-6-methylpyridazine
- 1121-79-5
- Biochemical Assay Reagents
- intermolecular interactions
- wide-band-gap indirect semiconductor
- UV-visible absorption
- 3-Chloro-6-methylpyridazinium cation
- monoclinic crystal structure
- DFT calculations
- organic-inorganic hybrid materials
- antimony trichloride
- green photoluminescence emission
- FT-IR spectroscopy
- Inhibitor
- inhibitor
- inhibit