Antifungal agent 108
Antifungal agent 108 (compound 14d), an original imidazo[1,2-b]pyridazine derivative, shows potent antifungal activity against Madurella mycetomatis (MM55 strain) with an IC50 of 0.9 μM. Antifungal agent 108 exhibits an IC50 of 14.3 μM on cell viability of NIH-3T3 murine fibroblast.
For research use only. We do not sell to patients.
- Formula: C22H22FN5OS
- Molecular Weight:423.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| NIH3T3 | IC50 |
10.7 μM
Compound: 14d
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Cytotoxicity against mouse NIH3T3 cells incubated for 5 days by MTT assay
Cytotoxicity against mouse NIH3T3 cells incubated for 5 days by MTT assay
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[PMID: 39142148] |
Chemical Information
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Molecular Weight 423.51
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Formula C22H22FN5OS
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SMILES
OCCN1CCN(C2=NN3C(C(C4=CSC=C4)=C2)=NC(C5=CC=CC(F)=C5)=C3)CC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antifungal agent 108 Related Classifications
HY-161921 Related Classifications
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