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synapsin I

" in MedChemExpress (MCE) Product Catalog:

By Targets:	CaMK (1) Epigenetic Reader Domain (1) ERK (1) Trk Receptor (1)
By Research Areas:	Neurological Disease (2)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P10282

Synapsin I-(3-13)	CaMK	Neurological Disease
Synapsin I-(3-13), a substrate for CaMK1, is a glycoprotein. Synapsin I is a phosphoprotein that coats the cytoplasmic side of synaptic vesicles and regulates their trafficking within nerve terminals .

HY-N20637

Polygalasaponin XXXII	ERK Epigenetic Reader Domain Trk Receptor	Neurological Disease
Polygalasaponin XXXII is an orally active cognitive enhancer. Polygalasaponin XXXII promotes the phosphorylation of ERK, CREB, Synapsin I and TrkB. Polygalasaponin XXXII enhances basal synaptic transmission. Polygalasaponin XXXII attenuates Scopolamine (HY-N0296)-induced cognitive impairment and improves hippocampus-dependent learning and memory abilities. Polygalasaponin XXXII can be used in research related to cognitive dysfunction .

Cat. No.	Product Name	Target	Research Area

HY-P10282

Synapsin I-(3-13)	CaMK	Neurological Disease
Synapsin I-(3-13), a substrate for CaMK1, is a glycoprotein. Synapsin I is a phosphoprotein that coats the cytoplasmic side of synaptic vesicles and regulates their trafficking within nerve terminals .

Polygalasaponin XXXII	Triterpenes Structural Classification Terpenoids Polygalaceae Polygala japonica Houtt. Plants Source Classification	ERK Epigenetic Reader Domain Trk Receptor
Polygalasaponin XXXII is an orally active cognitive enhancer. Polygalasaponin XXXII promotes the phosphorylation of ERK, CREB, Synapsin I and TrkB. Polygalasaponin XXXII enhances basal synaptic transmission. Polygalasaponin XXXII attenuates Scopolamine (HY-N0296)-induced cognitive impairment and improves hippocampus-dependent learning and memory abilities. Polygalasaponin XXXII can be used in research related to cognitive dysfunction .

Host:	Mouse (2) Rabbit (3)
Reactivity:	Human (5) Rat (5) Mouse (5) Monkey (2)
Application:	IHC-P (5) ICC/IF (3) IP (1) WB (5) FC (2) ELISA (3)
Isotype:	IgG (3) IgG1 (2)
Conjugation:	Non-conjugated (5)
Clonality:	Monoclonal (3) Recombinant (1)
Modification:	Phosphorylated (1) Unmodified (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P86325

	Synapsin I Antibody (YA6017) SYN1; synapsin-1; Brain protein 4.1; synapsin I	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Synapsin I Antibody (YA6017) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Synapsin I.

HY-P82119

	*Phospho-Synapsin* I (Ser9) Antibody (YA1864)** SYN1; synapsin-1; Brain protein 4.1; synapsin I	WB, IHC-P	Human, Mouse, Rat
	Phospho-Synapsin I (Ser9) Antibody (YA1864) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-Synapsin I (Ser9).

HY-P82119A

	*Phospho-Synapsin* I (Ser9) Antibody (YA1864)(PBS only)** SYN1; synapsin-1; Brain protein 4.1; synapsin I	WB, IHC-P	Human, Mouse, Rat
	Phospho-Synapsin I (Ser9) Antibody (YA1864) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-Synapsin I (Ser9).

HY-P84138

	Synapsin I Antibody (YA3835) SYNI; SYN1a; SYN1b	WB, IHC-P, ICC/IF, FC, ELISA	Human, Mouse, Monkey, Rat
	Synapsin I Antibody (YA3835) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Synapsin I.

HY-P84138A

	Synapsin I Antibody (YA3835)(PBS only) SYNI; SYN1a; SYN1b	WB, IHC-P, ICC/IF, FC, ELISA	Human, Mouse, Monkey, Rat
	Synapsin I Antibody (YA3835) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Synapsin I.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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