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triplet photosensitizer

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-126861
    2'-Deoxy-5-formylcytidine

    		Reactive Oxygen Species Others
    2'-Deoxy-5-formylcytidine is an effective internal triplet photosensitizer in DNA. 2'-Deoxy-5-formylcytidine could act as a new hot spot in DNA photodamage .
    2'-Deoxy-5-formylcytidine
  • HY-145538
    2'-Deoxyguanosine 5'-monophosphate disodium hydrate

    5'-Deoxyguanylic acid disodium hydrate

    		 DNA/RNA Synthesis Others
    2'-Deoxyguanosine 5'-monophosphate (5'-Deoxyguanylic acid; dGMP) disodium hydrate is an oxidizable target of the photosensitizer pterin (PT) and can be used to evaluate the photosensitizing properties of biopterins (such as Bip, Fop and Cap) . Pterin causes a photosensitive reaction of dGMP under UV-A radiation, causing damage to DNA molecules. There are two main mechanisms for the photosensitive oxidation of purine nucleotides by pterin in vitro: one is the hydrogen abstraction reaction of electron transfer from dGMP to the triplet excited state of pterin (type I mechanism), and the other is the interaction between dGMP and pterin. The reaction produces singlet molecular oxygen (1O2) (Type II mechanism) .
    2'-Deoxyguanosine 5'-monophosphate disodium hydrate

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