5-Methyl-1H-benzotriazole (Synonyms: 5-Methylbenzotriazole)

Cat. No.: HY-W086988 Purity: 99.96%: Data Sheet
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5-Methyl-1H-benzotriazole (5-Methylbenzotriazole) is a benzotriazole derivative, and serves as a key building block for ultraviolet absorbers and light stabilizers. 5-Methyl-1H-benzotriazole reduces the photosensitizing ability of nitrate and dissolved organic matter (DOM), enhances the persistence of microorganic pollutants, inhibits the photodegradation of DOM and drug residues, and quenches the triplet excited states of DOM and methotrexate substructures. 5-Methyl-1H-benzotriazole acts as a corrosion inhibitor for copper and copper alloys, and is present in formulations of anti-icing fluids, dishwasher detergents, aircraft deicing fluids and automotive antifreezes.

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5-Methyl-1H-benzotriazole Chemical Structure

CAS No. : 136-85-6

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
10 g	In-stock	Estimated Time of Arrival: December 31
25 g	In-stock	Estimated Time of Arrival: December 31
50 g	Get quote

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Other Forms of 5-Methyl-1H-benzotriazole:

5-Methyl-1H-benzotriazole-d₆ Get quote
5-Methyl-1H-benzotriazole (Standard) Get quote

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Purity & Documentation
References
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Description

In Vitro

5-Methyl-1H-benzotriazole is widely found in industrial wastewater^[1].
5-Methyl-1H-benzotriazole (0.150 μM; up to 50 h of irradiation) undergoes direct photolysis in DI water with a half-life of 14 h, and its photolysis rate slows significantly in river water, resulting in a longer half-life of 24 h^[1].
5-Methyl-1H-benzotriazole (1.0 mg/L; up to 9 h) undergoes first-order photodegradation in aqueous solutions under 254 nm UV irradiation (half-life 7.1 h in pure water at pH 7), with rates decreasing with increasing pH, salinity, Fe³⁺ concentration, and humic acid concentration, and slight inhibition from Cu²⁺^[2].
5-Methyl-1H-benzotriazole (1.0 mg/L; 9 h) produces two primary photoproducts, 4-methylaniline and N,N-diethylaniline-p-toluidine, via initial N-N and N-NH bond scission followed by subsequent transformation steps when exposed to UV irradiation in aqueous solutions^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

133.15

Formula

C₇H₇N₃

CAS No.

136-85-6

Appearance

Solid

Color

White to off-white

SMILES

CC1=CC=C2NN=NC2=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (751.03 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	7.5103 mL	37.5516 mL	75.1033 mL
5 mM	1.5021 mL	7.5103 mL	15.0207 mL
10 mM	0.7510 mL	3.7552 mL	7.5103 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.96%

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Data Sheet (274 KB) SDS (396 KB)

COA (249 KB) HNMR (113 KB) RP-HPLC (198 KB)

Handling Instructions (2659 KB)

References

[1]. Chung KH, et al. The persistence and photostabilizing characteristics of benzotriazole and 5-methyl-1H-benzotriazole reduce the photochemical behavior of common photosensitizers and organic compounds in aqueous environments. Environ Sci Pollut Res Int. 2018;25(6):5911-5920. [Content Brief]

[2]. Liu YS, et al. Photo transformation of 5-methylbenzotriazole and 5-chlorobenzotriazole by UV irradiation: Influences of pH, salinity, metal species and humic acid. Environ Res. 2021;194:110678. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	7.5103 mL	37.5516 mL	75.1033 mL	187.7582 mL
	5 mM	1.5021 mL	7.5103 mL	15.0207 mL	37.5516 mL
	10 mM	0.7510 mL	3.7552 mL	7.5103 mL	18.7758 mL
	15 mM	0.5007 mL	2.5034 mL	5.0069 mL	12.5172 mL
	20 mM	0.3755 mL	1.8776 mL	3.7552 mL	9.3879 mL
	25 mM	0.3004 mL	1.5021 mL	3.0041 mL	7.5103 mL
	30 mM	0.2503 mL	1.2517 mL	2.5034 mL	6.2586 mL
	40 mM	0.1878 mL	0.9388 mL	1.8776 mL	4.6940 mL
	50 mM	0.1502 mL	0.7510 mL	1.5021 mL	3.7552 mL
	60 mM	0.1252 mL	0.6259 mL	1.2517 mL	3.1293 mL
	80 mM	0.0939 mL	0.4694 mL	0.9388 mL	2.3470 mL
	100 mM	0.0751 mL	0.3755 mL	0.7510 mL	1.8776 mL

5-Methyl-1H-benzotriazole Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5-Methyl-1H-benzotriazole136-85-65-MethylbenzotriazoleBiochemical Assay Reagentscopper alloystriplet-excited-state DOMdissolved organic mattermethotrexatemicro-organic pollutantsbenzotriazole derivativeDahan Riverpharmaceutical residuecopperTaipei City river watersInhibitorinhibitorinhibit

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