2'-Deoxyguanosine 5'-monophosphate disodium hydrate
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2'-Deoxyguanosine 5'-monophosphate (5'-Deoxyguanylic acid; dGMP) disodium hydrate is an oxidizable target of the photosensitizer pterin (PT) and can be used to evaluate the photosensitizing properties of biopterins (such as Bip, Fop and Cap) . Pterin causes a photosensitive reaction of dGMP under UV-A radiation, causing damage to DNA molecules. There are two main mechanisms for the photosensitive oxidation of purine nucleotides by pterin in vitro: one is the hydrogen abstraction reaction of electron transfer from dGMP to the triplet excited state of pterin (type I mechanism), and the other is the interaction between dGMP and pterin. The reaction produces singlet molecular oxygen (1O2) (Type II mechanism).
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- Purity : 99.0%
- CAS No.: 146877-98-7
- Formula: C10H14N5O7.H2O.2Na
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All DNA/RNA Synthesis Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 146877-98-7
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Appearance Solid
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Formula C10H14N5O7.H2O.2Na
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Color White to off-white
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SMILES
O[C@H]1C[C@H](N2C=NC3=C2NC(N)=NC3=O)O[C@@H]1COP(O[Na])(O[Na])=O.[x].O
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Synonyms
5'-Deoxyguanylic acid disodium hydrate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)