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visual

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Calcium Channel (1) Endogenous Metabolite (1) Fluorescent Dye (2) p38 MAPK (1) Potassium Channel (2)
By Research Areas:	Inflammation/Immunology (1) Metabolic Disease (2) Neurological Disease (4)

9

Inhibitors & Agonists

3

Biochemical Assay Reagents

1

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-19720

Emixustat

ACU-4429
Others Metabolic Disease

Emixustat, a novel visual cycle modulator, is an inhibitor of the visual cycle isomerase with an IC₅₀ value of 4.4 nM in vitro.

Ulixacaltamide Z944	Calcium Channel	Neurological Disease
Ulixacaltamide (Z944) is an orally active T-type calcium channel antagonist that rescues impairments in crossmodal and visual recognition memory.

DAD	Potassium Channel	Neurological Disease
DAD is a type of ion channel blocker that blocks voltage-gated potassium channels. DAD is a third-generation photoswitch that responds to visible light. DAD has the potential for restoring visual function .

DAD dichloride	Potassium Channel	Neurological Disease
DAD dichloride is a type of ion channel blocker that blocks voltage-gated potassium channels. DAD dichloride is a third-generation photoswitch that responds to visible light. DAD dichloride has the potential for restoring visual function .

Hydroxynaphthol Blue	Fluorescent Dye	Others
Hydroxynaphthol Blue enables visual tube closure detection. Hydroxynaphthol Blue shows high specificity for the gene encoding Ara h 1 for visual field detection of peanut allergens .

MSC 2032964A	p38 MAPK	Inflammation/Immunology
MSC 2032964A is an orally active, selective inhibitor for apoptosis signal-regulating kinase 1(ASK1) with IC₅₀ of 96 nM. MSC 2032964A preserves the visual responses in EAE mice model and exhibits potency in ameliorating the neuroinflammation .

DL-AP4 2-Amino-4-phosphonobutyric acid
DL-AP4 (2-Amino-4-phosphonobutyric acid) is a glutamate antagonist. DL-AP4 behaves as a competitive inhibitor of glutamate binding with an apparent K_d of 66 μM. DL-AP4 can be used for the research of central nervous system and visual system .

α-Naphtholbenzein p-Naphtolbenzein	Fluorescent Dye	Others
α-Naphtholbenzein (p-Naphtolbenzein) is a dye. α-Naphtholbenzein can be used as a pH indicator. α-Naphtholbenzein has a visual transition from yellow (pH0-8.2) to turquoise (pH10). α-Naphtholbenzein is often used during sequential injection analysis technique done for acid-base titrations .

All-trans-retinal	Endogenous Metabolite Apoptosis	Metabolic Disease
All-trans-retinal is an vitamin A metabolite in the retina, and is produced following photo-isomerization of the visual chromophore 11-cis-Retinal. All-trans-retinal is cleared from photoreceptors by ATP-binding cassette transporter (ABCA4) and all-trans-retinol dehydrogenase (RDH). All-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis .

Cat. No.	Product Name	Type

ADTN hydrobromide	Biochemical Assay Reagents
ADTN hydrobromide is a long-acting dopamine agonist. ADTN hydrobromide significantly decreases the behavioral visual threshold of DA-IPC-depleted zebrafish .

Hydroxynaphthol Blue	Biochemical Assay Reagents
Hydroxynaphthol Blue enables visual tube closure detection. Hydroxynaphthol Blue shows high specificity for the gene encoding Ara h 1 for visual field detection of peanut allergens .

α-Naphtholbenzein p-Naphtolbenzein	Biochemical Assay Reagents
α-Naphtholbenzein (p-Naphtolbenzein) is a dye. α-Naphtholbenzein can be used as a pH indicator. α-Naphtholbenzein has a visual transition from yellow (pH0-8.2) to turquoise (pH10). α-Naphtholbenzein is often used during sequential injection analysis technique done for acid-base titrations .

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