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11

Inhibitors & Agonists

1

Screening Libraries

1

Fluorescent Dye

2

Biochemical Assay Reagents

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-14559
    PRX-07034 hydrochloride

    		5-HT Receptor Neurological Disease
    PRX-07034 hydrochloride is a highly selective and potent 5-HT6 receptor antagonist with a Ki= 4-8 nM and an IC50 of 19 nM. PRX-07034 can be used for the research of enhancing working memory and cognitive flexibility .
    PRX-07034 hydrochloride
  • HY-B0564
    Sodium nitroprusside
    4 Publications Verification

    Ro 21-2498

    		 Others Cardiovascular Disease Cancer
    Sodium nitroprusside (Ro 21-2498) is a potent vasodilator working through releasing NO spontaneously in blood.
    Sodium nitroprusside
  • HY-D0866
    ACES

    N-(2-Acetamido)-2-aminoethanesulfonic acid

    		 Biochemical Assay Reagents Others
    ACES (N-(2-Acetamido)-2-aminoethanesulfonic acid) is a zwitterionic buffer. The working pH range of ACES buffer is 6.8-7.2 .
    ACES
  • HY-160505
    RO-275

    		HCN Channel Neurological Disease
    RO-275 (compound 29) is a potent, selective and orally active HCN1 inhibitor with IC50 values of 0.046, 14.3, 4.6, 13.9 µM for HCN1, HCN2, HCN3, HCN4, respectively. RO-275 rescues decremented working memory. RO-275 has the potential for the research of cognitive dysfunction in brain disorder .
    RO-275
  • HY-U00172
    Ipramidil

    C80-1324

    		 Others Cardiovascular Disease
    Ipramidil (C80-1324) is a furoxan compound. Ipramidil (C80-1324) reveals marked dilator activity in the coronary circulation of isolated working hearts.
    Ipramidil
  • HY-147877
    Topoisomerase II inhibitor 12

    		Topoisomerase Cancer
    Topoisomerase II inhibitor 12 (Compound 8c) is a topoisomerase II (topo II) inhibitor, working as a DNA non-intercalator. Topoisomerase II inhibitor 12 shows antineoplastic activity .
    Topoisomerase II inhibitor 12
  • HY-D0874
    HEPPSO

    		Biochemical Assay Reagents Others
    HEPPSO is a zwitterionic buffer. The working pH range of HEPPSO buffer is 7.1-8.5. HEPPSO displays relatively high ability to bind copper(II), has a pKa of 7.84 at 2.0 mM buffer concentration .
    HEPPSO
  • HY-112781
    Pesampator

    PF-04958242

    		 iGluR Neurological Disease
    Pesampator (PF-04958242) is a potent and highly selective positive allosteric modulator of AMPA receptor (an AMPA potentiator) with an EC50 of 310 nM and a Ki of 170 nM .
    Pesampator
  • HY-D2299
    AIE-ER

    		Fluorescent Dye Metabolic Disease Cancer
    AIE-ER is a specific endoplasmic reticulum (ER) fluorescent probe (green channel: λex=405 nm, λem=450~650 nm) that exhibits remarkable photostability, high brightness, and low working concentration. AIE-ER may provide an avenue for studying diseases related to the endoplasmic reticulum .
    AIE-ER
  • HY-D0876
    POPSO

    		Biochemical Assay Reagents Others
    POPSO is a zwitterionic buffer, increases osmolality and shows marked inhibition of anion uniport. POPSO inhibits chloride uniport with an IC50 value of 24 mM. POPSO enhances copper uptake and toxicity in alga, impairs mitochondrial inner membrane. The working pH range of POPSO sesquisodium salt is 7.2-8.5 .
    POPSO
  • HY-149975
    AMPA receptor modulator-4

    		iGluR Neurological Disease
    AMPA receptor modulator-4, a 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide (BTD), is an orally active positive allosteric modulator of the AMPA receptors (AMPAR PAMs). AMPA receptor modulator-4 can cross the blood-brain barrier. AMPA receptor modulator-4 increases the cognition performance and improves working memory performance in mice .
    AMPA receptor modulator-4

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