ACES (Synonyms: N-(2-Acetamido)-2-aminoethanesulfonic acid)

Cat. No.: HY-D0866 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

ACES (N-(2-Acetamido)-2-aminoethanesulfonic acid) is a zwitterionic buffer. The working pH range of ACES buffer is 6.8-7.2.

For research use only. We do not sell to patients.

ACES Chemical Structure

CAS No. : 7365-82-4

Size	Price	Stock	Quantity
Solid + Solvent
10 mM * 1 mL in Water ready for reconstitution	USD 33	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	USD 33	In-stock	Estimated Time of Arrival: December 31
Solid
500 mg	USD 30	In-stock	Estimated Time of Arrival: December 31
1 g		Get quote
5 g		Get quote

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Description

ACES (N-(2-Acetamido)-2-aminoethanesulfonic acid) is a zwitterionic buffer. The working pH range of ACES buffer is 6.8-7.2^[1]^[2].

Clinical Trial

Molecular Weight

182.20

Formula

C₄H₁₀N₂O₄S

CAS No.

7365-82-4

Appearance

Solid

Color

White to off-white

SMILES

O=C(N)CNCCS(=O)(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : 41.67 mg/mL (228.70 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.4885 mL	27.4424 mL	54.8847 mL
5 mM	1.0977 mL	5.4885 mL	10.9769 mL
10 mM	0.5488 mL	2.7442 mL	5.4885 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 16.67 mg/mL (91.49 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (269 KB) SDS (416 KB)

COA (245 KB) HNMR (233 KB)

Handling Instructions (2659 KB)

References

[1]. Melissa D Mertzman, et al. Effect of surfactant concentration and buffer selection on chromatographic figures of merit in chiral microemulsion electrokinetic chromatography. Electrophoresis. 2004 Oct;25(18-19):3247-56. [Content Brief]

[2]. Rabindra N Roy, et al. Buffer Standards for the Physiological pH of the Zwitterionic Compound, ACES from 5 to 55°C. J Solution Chem. 2009 Apr 1;38(4):471-483. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	5.4885 mL	27.4424 mL	54.8847 mL	137.2119 mL
	5 mM	1.0977 mL	5.4885 mL	10.9769 mL	27.4424 mL
	10 mM	0.5488 mL	2.7442 mL	5.4885 mL	13.7212 mL
	15 mM	0.3659 mL	1.8295 mL	3.6590 mL	9.1475 mL
	20 mM	0.2744 mL	1.3721 mL	2.7442 mL	6.8606 mL
	25 mM	0.2195 mL	1.0977 mL	2.1954 mL	5.4885 mL
	30 mM	0.1829 mL	0.9147 mL	1.8295 mL	4.5737 mL
	40 mM	0.1372 mL	0.6861 mL	1.3721 mL	3.4303 mL
	50 mM	0.1098 mL	0.5488 mL	1.0977 mL	2.7442 mL
	60 mM	0.0915 mL	0.4574 mL	0.9147 mL	2.2869 mL
	80 mM	0.0686 mL	0.3430 mL	0.6861 mL	1.7151 mL
	100 mM	0.0549 mL	0.2744 mL	0.5488 mL	1.3721 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

ACES Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ACES7365-82-4N-(2-Acetamido)-2-aminoethanesulfonic acidBiochemical Assay ReagentsZwitterionicbufferInhibitorinhibitorinhibit

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