2. Metabolic Enzyme/Protease
  3. ANGPTL
  4. Solbinsiran sodium

Solbinsiran sodium is a siRNA targeted to hepatic ANGPTL3.

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RNA, ([4'-de(hydroxymethyl)-4'-[(hydroxymethoxyphosphinyl)methoxy]]Um-sp-(2'-deoxy-2'-fluoro)G-sp-(2'-deoxy-2'-fluoro)U-sp-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'-fluoro)U-Am-(2'-deoxy-2'-fluoro)A-Cm-Cm-(2'-deoxy-2'-fluoro)U-Um-Cm-Cm-(2'-deoxy-2'-fluoro)A-Um-Um-Um-Um-Gm-Am-sp-Gm-sp-Gm), sodium salt, complex with RNA (Um-sp-Cm-Am-Am-Am-Am-Um-(2'-deoxy-2'-fluoro)G-(2'-deoxy-2'-fluoro)G-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'-fluoro)A-Gm-Gm-Um-Um-Am-Um-Am-Cm-Am-Gm-Cm-Am-Gm-Cm-Cm-Gm-[2'-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]A-[2'-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]A-[2'-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]A-Gm-Gm-Cm-Um-Gm-Cm) sodium salt (1:22:1:35)

Solbinsiran sodium Estructura química

No. CAS : 2707429-60-3

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Solbinsiran sodium Related Antibodies

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ANGPTL3 ANGPTL4 ANGPTL8

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Solbinsiran sodium Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Solbinsiran2707429-60-3LY3561774LY 3561774LY-3561774ANGPTLAngiopoietin-like proteinInhibitorinhibitorinhibit

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