1. Cell Cycle/DNA Damage
  2. STK33
  3. STK33-IN-1

STK33-IN-1 (compound 1) is a STK33 inhibitor, with an IC50 of 7 nM.

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STK33-IN-1

STK33-IN-1 Chemische Struktur

CAS. Nr. : 1404437-49-5

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Beschreibung

STK33-IN-1 (compound 1) is a STK33 inhibitor, with an IC50 of 7 nM[1].

IC50 & Target

IC50: 7 nM (STK33)[1].

In Vitro

STK33-IN-1 (compound 1) is 2-fold selective for Aurora-B (AurB) versus STK33. STK33-IN-1 (compound 1) has proven unsuccessful in selectively killing KRAS-dependent cancer cell lines[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molekulargewicht

445.52

Formel

C24H27N7O2

CAS. Nr.
SMILES

COC(C=C1)=CC=C1N2N=CC3=CN=C(NC4=CC=C(N5CCN(C)CC5)C(OC)=C4)N=C32

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

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STK33-IN-1
Art. -Nr.:
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