tert-Butyl 4-(methylamino)butylcarbamate

Cat. No.: HY-40180: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

tert-Butyl 4-(methylamino)butylcarbamate is a PROTAC linker that can be used in the synthesis of PROTACs.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

tert-Butyl 4-(methylamino)butylcarbamate 화학구조

CAS No. : 874831-66-0

사이즈	재고	수량
무료 샘플 (0.1 - 0.2 mg)	지금 신청하기
무료 샘플 (0.1 - 0.2 mg)	지금 신청하기
250 mg	해외재고보유	Estimated Time of Arrival: December 31
500 mg	해외재고보유	Estimated Time of Arrival: December 31
1 g	해외재고보유	Estimated Time of Arrival: December 31
5 g	해외재고보유	Estimated Time of Arrival: December 31
10 g	해외재고보유	Estimated Time of Arrival: December 31
50 g	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

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Biological Activity
순도&문서
고객리뷰

제품 설명

tert-Butyl 4-(methylamino)butylcarbamate is a PROTAC linker that can be used in the synthesis of PROTACs.

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E1018 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

202.30

화학식

C₁₀H₂₂N₂O₂

CAS No.

874831-66-0

Appearance

Solid

Color

Colorless to light yellow

SMILES

O=C(OC(C)(C)C)NCCCCNC

선적

Room temperature in continental US; may vary elsewhere.

보관

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

용액&용해도

In Vitro:

DMSO : ≥ 100 mg/mL (494.32 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.9432 mL	24.7158 mL	49.4315 mL
5 mM	0.9886 mL	4.9432 mL	9.8863 mL
10 mM	0.4943 mL	2.4716 mL	4.9432 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: 99.77%

Select Batch:

Data Sheet (239 KB) SDS (480 KB)

COA (242 KB) HNMR (112 KB) LCMS (298 KB) GC (213 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.9432 mL	24.7158 mL	49.4315 mL	123.5788 mL
	5 mM	0.9886 mL	4.9432 mL	9.8863 mL	24.7158 mL
	10 mM	0.4943 mL	2.4716 mL	4.9432 mL	12.3579 mL
	15 mM	0.3295 mL	1.6477 mL	3.2954 mL	8.2386 mL
	20 mM	0.2472 mL	1.2358 mL	2.4716 mL	6.1789 mL
	25 mM	0.1977 mL	0.9886 mL	1.9773 mL	4.9432 mL
	30 mM	0.1648 mL	0.8239 mL	1.6477 mL	4.1193 mL
	40 mM	0.1236 mL	0.6179 mL	1.2358 mL	3.0895 mL
	50 mM	0.0989 mL	0.4943 mL	0.9886 mL	2.4716 mL
	60 mM	0.0824 mL	0.4119 mL	0.8239 mL	2.0596 mL
	80 mM	0.0618 mL	0.3089 mL	0.6179 mL	1.5447 mL
	100 mM	0.0494 mL	0.2472 mL	0.4943 mL	1.2358 mL