Tos-aminoxy-Boc-PEG4-Tos

Name: Tos-aminoxy-Boc-PEG4-Tos
Brand: MedChemExpress
SKU: HY-140380
Rating: 4.5 (0 reviews)

Cat. No.: HY-140380: Data Sheet Handling Instructions
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Tos-aminoxy-Boc-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Tos-aminoxy-Boc-PEG4-Tos 화학구조

CAS No. : 1817735-42-4

사이즈	재고	수량
5 mg	견적 받기 2 - 3 weeks 1 - 2 Weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
10 mg	견적 받기 2 - 3 weeks 1 - 2 Weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
25 mg	견적 받기 2 - 3 weeks 1 - 2 Weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 mg	견적 받기 2 - 3 weeks 1 - 2 Weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 mg	견적 받기 2 - 3 weeks 1 - 2 Weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
200 mg	견적 받기
500 mg	견적 받기

Synthetic products have potential research and development risk.

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* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

Tos-aminoxy-Boc-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs^[1].

IC₅₀ & Target

PEGs

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

617.73

화학식

C₂₇H₃₉NO₁₁S₂

CAS No.

1817735-42-4

SMILES

O=S(N(OCCOCCOCCOCCOS(=O)(C1=CC=C(C)C=C1)=O)C(OC(C)(C)C)=O)(C2=CC=C(C)C=C2)=O

선적

Room temperature in continental US; may vary elsewhere.

보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 [Content Brief]