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  3. TRITC-dextran, MW 70000

TRITC-dextran, MW 70000  (Synonyms: Tetramethyl rhodamine isothiocyanate glucan, MW 70000)

Cat. No.: HY-158082C
Instrucciones de manejo Technical Support

TRITC-dextran MW 70000 (Tetramethyl rhodamine isothiocyanate glucan, MW 70000) is a fluorescent dye with a molecular weight of 70 kD. The excitation wavelength of TRITC-dextran MW 70000 is 555 nm, and its emission wavelength is 570 nm. TRITC-dextran MW 70000 is used for drug delivery because TRITC maintains stability over a wide pH range (i.e., pH 2-11) and exhibits photobleaching resistance.

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Revisión del cliente

Based on 2 publication(s) in Google Scholar

Other Forms of TRITC-dextran, MW 70000:

Top Publications Citing Use of Products
Bio/Physico-chemical Assay

    TRITC-dextran, MW 70000 purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Aug 18:e08613.  [Abstract]

    TRITC-dextran, MW 70000 (TMR‐Dextran; 20 ng/mL; 100 µL;0, 30, 60, and 120 min) in HUVEC monolayers treated with indicated sEVs. The permeability of HUVEC monolayers to TRITC-dextran, MW 70000 (TMR‐Dextran; 20 ng/mL; 100 µL;0, 30, 60, and 120 min) increased after exposure to CLTB‐NC‐sEVs and CLTB‐OE‐sEVs.

    TRITC-dextran, MW 70000 purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Aug 18:e08613.  [Abstract]

    sEV-CLTB reduced TMR-dextran leakage. TRITC-dextran, MW 70000 (TMR‐Dextran; 20 ng/mL; 100 µL;0, 30, 60, and 120 min) permeability assay measuring vascular leakage in HUVECs. Fluorescence intensity in the lower chamber was quantified.
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    Descripciòn

    TRITC-dextran MW 70000 (Tetramethyl rhodamine isothiocyanate glucan, MW 70000) is a fluorescent dye with a molecular weight of 70 kD. The excitation wavelength of TRITC-dextran MW 70000 is 555 nm, and its emission wavelength is 570 nm. TRITC-dextran MW 70000 is used for drug delivery because TRITC maintains stability over a wide pH range (i.e., pH 2-11) and exhibits photobleaching resistance[1].

    In Vitro

    Paracellular Permeability Assay[1]
    1. Add TRITC-dextran MW 70000 (20 mg/mL, 100 μL) to the basal medium in the upper chamber of a transwell (pore size 0.4 μm).
    2. Collect the medium from the lower transwell chamber at 0, 30, 60, and 120 minutes.
    3. Measure the fluorescence signal (Ex=544 nm, Em=570 nm).
    4. Calculate the concentration of TRITC-dextran MW 70000 based on the fluorescence intensity.
    5. Calculate the permeability rate.

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Peso molecular

    70000.00

    Appearance

    Solid

    Color

    Purple to purplish red

    SMILES

    [TRITC-dextran, MW 70000]

    Envío

    Room temperature in continental US; may vary elsewhere.

    Almacenamiento

    4°C, protect from light

    *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

    Solvente y solubilidad
    In Vitro: 

    H2O : 50 mg/mL (0.71 mM; Need ultrasonic)

    • Calculadora de molaridad

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    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start)

    C1

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    Volume (start)

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    =
    Concentration (final)

    C2

    ×
    Volume (final)

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    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

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    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
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    Working solution concentration: mg/mL
    This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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    Inquiry Information

    Nombre del producto:
    TRITC-dextran, MW 70000
    Cat. No.:
    HY-158082C
    Cantidad:
    MCE Japan Authorized Agent: