TTHA 

TTHA is an aminopolycarboxylic acid chelating agent with preferential affinity for lighter (lower atomic number) rare earth element (REE) ions. TTHA binds to REE ions through chelation as the primary coordination mechanism^[1].

TTHA (2 weeks) forms a nine-coordinate complex with Dy³⁺ under neutral pH (6.5) conditions, in which one carboxylate group is protonated and unbound^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

494.45

C₁₈H₃₀N₄O₁₂

869-52-3

Solid

White to off-white

O=C(CN(CCN(CCN(CCN(CC(O)=O)CC(O)=O)CC(O)=O)CC(O)=O)CC(O)=O)O

Room temperature in continental US; may vary elsewhere.

Store at room temperature, keep dry and cool

*In solvent : -80°C, 6 months; -20°C, 1 month (Store at room temperature, keep dry and cool)

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

• [1]. Polido Legaria E, et al. Toward Molecular Recognition of REEs: Comparative Analysis of Hybrid Nanoadsorbents with the Different Complexonate Ligands EDTA, DTPA, and TTHA. Inorg Chem. 2017;56(22):13938-13948.  [Content Brief]