1. Immunology/Inflammation
  2. PGE synthase
  3. U-51605

U-51605 is a platelet aggregation inhibitor and inhibits thromboxane synthesis. U-51605 is also a prostaglandin I2 synthase inhibitor and can inhibit the retinal vasodilation response induced by NO donors (such as NOR3).

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U-51605

U-51605 Estructura química

No. CAS : 64192-56-9

Tamaño Precio Stock Cantidad
100 μg Obtener un presupuesto 2 - 3 weeks 4 - 5 weeks 5 - 6 weeks 1 - 2 weeks
500 μg Obtener un presupuesto 2 - 3 weeks 4 - 5 weeks 5 - 6 weeks 1 - 2 weeks
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Descripciòn

U-51605 is a platelet aggregation inhibitor and inhibits thromboxane synthesis. U-51605 is also a prostaglandin I2 synthase inhibitor and can inhibit the retinal vasodilation response induced by NO donors (such as NOR3)[1][2].

IC50 & Target

Prostaglandin I2 synthase inhibitor 9α[2]

In Vitro

U-51605 (3 μM) inhibits acetylcholine-induced endothelium-dependent contraction[1].
U-51605 (0.5, 1, 3 and 10 μM) increases in acetylcholine-induced release of PGE2 and PGF2α[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

332.48

Fòrmula

C20H32N2O2

No. CAS
SMILES

OC(CCC/C=C\C[C@@H]1[C@H]([C@@]2([H])C[C@]1([H])N=N2)/C=C/CCCCCC)=O

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
U-51605
Cat. No.:
HY-129199
Cantidad:
MCE Japan Authorized Agent: