2. Metabolic Enzyme/Protease
  3. Dihydroorotate Dehydrogenase
  4. UCK2 Inhibitor-2

UCK2 Inhibitor-2 is a non-competitive uridine-cytidine kinase 2 (UCK2) inhibitor with an IC50 value of 3.8 µM. UCK2 Inhibitor-2 can suppress uridine salvage in cells.

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UCK2 Inhibitor-2

UCK2 Inhibitor-2 Estructura química

No. CAS : 866842-71-9

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UCK2 Inhibitor-2 Related Antibodies

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Descripciòn

UCK2 Inhibitor-2 is a non-competitive uridine-cytidine kinase 2 (UCK2) inhibitor with an IC50 value of 3.8 µM. UCK2 Inhibitor-2 can suppress uridine salvage in cells[1].

IC50 & Target

IC50: 3.8 µM (UCK2)[1]
In Vitro

UCK2 Inhibitor-2 (compound 20874830) shows 52% inhibition of uridine salvage in K562 cells at a concentration of 50 µM. The inhibition of DHODH increases uridine salvage, while, UCK2 inhibitor UCK2 Inhibitor-2 (compound 20874830) can suppress this increase[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

UCK2 Inhibitor-2 Related Antibodies
Peso molecular

497.56

Fòrmula

C28H23N3O4S
No. CAS
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(C1=CC(NC(CSC2=C3CC4=C(C(C)=CC=C4)OC3=NC(C5=CC=C(C)C=C5)=N2)=O)=CC=C1)O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Pureza y Documentación
Referencias
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UCK2 Inhibitor-2 Related Classifications

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

UCK2 Inhibitor-2866842-71-9Dihydroorotate DehydrogenaseDHODHuridine salvageUCK2Inhibitorinhibitorinhibit

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Nombre del producto:
UCK2 Inhibitor-2
Cat. No.:
HY-148395
Cantidad:
MCE Japan Authorized Agent:

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