WIN 51708

Art. -Nr.: HY-105346 Reinheit: 99.70%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

WIN 51708 is a nonpeptide antagonist of neurokinin (NK)-1 receptor. WIN 51708 has a higher affinity for the rat NK-1 receptor compared to the human NK-1 receptor.

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WIN 51708 Chemische Struktur

CAS. Nr. : 144177-30-0

Größe	Verfügbarkeit	Menge
1 mg	Auf Lager	Estimated Time of Arrival: December 31
5 mg	Auf Lager	Estimated Time of Arrival: December 31
10 mg	Auf Lager	Estimated Time of Arrival: December 31
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100 mg	Angebot einholen

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This product is a controlled substance and not for sale in your territory.

Spezialitätsempfehlungen

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Alle Neurokinin Receptor Isoform-spezifische Produkte anzeigen:

Alle Isoformen anzeigen

NK1R NK2R NK3R

Biologische Aktivität
Reinheit & Dokumentation
Verweise
Kundenbewertung

Beschreibung

WIN 51708 is a nonpeptide antagonist of neurokinin (NK)-1 receptor. WIN 51708 has a higher affinity for the rat NK-1 receptor compared to the human NK-1 receptor^[1].

Molekulargewicht

439.59

Formel

C₂₉H₃₃N₃O

CAS. Nr.

144177-30-0

Appearance

Solid

Color

Light yellow to yellow

SMILES

C[C@@]12[C@]3([H])[C@](CC[C@@]1([H])CC4=NC5=NC6=CC=CC=C6N5C=C4C2)([H])[C@@]7([H])[C@](CC3)([C@@](O)(CC7)C#C)C

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Reinheit & Dokumentation

Purity: 99.70%

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Data Sheet (269 KB) SDS (252 KB)

COA (252 KB) HNMR (181 KB) LCMS (155 KB)

Handling Instructions (2659 KB)

Verweise

[1]. Sachais BS, et al. Both extracellular and transmembrane residues contribute to the species selectivity of the neurokinin-1 receptor antagonist WIN 51708. Mol Pharmacol. 1994 Jul;46(1):122-8. [Content Brief]

WIN 51708 Related Classifications

Neurological Disease

Molaritätsrechner
Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Diese Gleichung wird häufig abgekürzt als: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

WIN 51708144177-30-0WIN51708WIN-51708Neurokinin ReceptorNK receptorTachykinin receptorNonpeptidehuman NK-1rat NK-1 receptorInhibitorinhibitorinhibit

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