α-Glucosidase, rice 

α-Glucosidase, rice is a GH31 glycoside hydrolase in rice seeds, with high selectivity for α-1,4-glycosidic bonds. α-Glucosidase, rice can be inhibited by rice husk extracts (IC₅₀ = 1.25 μg/mL) and steroidal components (IC₅₀ = 1.83 μg/mL). α-Glucosidase, rice exists in two major isoforms, among which isoform II is more sensitive to inhibitors. α-Glucosidase, rice can directly bind to and degrade starch granules in rice seeds. α-Glucosidase, rice can form ONG2-I and ONG2-II via post-translational proteolysis. α-Glucosidase, rice can be used in type 2 diabetes research^[1][2][3].

α-Glucosidase, rice (5 mg/mL oligosaccharides/heteroglucosides, 2 mg/mL polysaccharides; 10 min at 37°C) shows a strong preference for α-1,4-linked glycosides^[1].
α-Glucosidase, rice (0.5% substrate; 5 min preincubation, 10 min incubation) isoforms α-glucosidase I and α-glucosidase II exhibit maximum activity toward maltose at 55 °C and maximum activity toward soluble starch at 50 °C.^[1].
α-Glucosidase, rice (100 mM Tris, 100 mM erythritol; 20 min at 37°C) are inhibited by 100 mM Tris and 100 mM erythritol, with both α-glucosidase I and α-glucosidase II affected. Among them, α-glucosidase II is more sensitive to these two inhibitors than α-glucosidase I^[1].
α-Glucosidase, rice exists as two isoforms, ONG2-I and ONG2-II, which directly bind to and degrade starch granules; ONG2-II shows stronger binding ability and faster glucose release rate. Both isoforms share identical substrate specificity and kinetic characteristics, have an optimal pH of 4.5, and exhibit thermostability up to 40 °C.^[2].
α-Glucosidase, rice is inhibited by rice husk extracts (IC₅₀ = 1.25 μg/mL) and steroidal components isolated from rice husks (IC₅₀ = 1.83 μg/mL)^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

9001-42-7

Liquid

Colorless to light yellow

[a-Glucosidase, rice]

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Takahashi N. Studies on α-Glucosidase in Rice: Part I. Isolation and Some Properties of α-Glucosidase I and α-Glucosidase II. Agric Biol Chem. 1971;35(13):2015-2024.

  [2]. Nakai H, et al. Multiple forms of alpha-glucosidase in rice seeds (Oryza sativa L., var Nipponbare). Biochimie. 2007;89(1):49-62.

  [3]. Wang WL, et al. α-Glucosidase inhibitors from the husks of rice Oryza sativa L. Fitoterapia. 2023;171:105688.