1. Neuronal Signaling
  2. Amyloid-β
  3. β-Amyloid (22-35) (TFA)

β-Amyloid (22-35) (TFA) (Synonyms: Amyloid β-Protein (22-35) (TFA))

Cat. No.: HY-P1474A
Handling Instructions

β-Amyloid 22-35 (Amyloid β-Protein 22-35) TFA, the residues 22-35 fragment ofβ-amyloid protein, has a cytotoxic effect on cultured neurons from the rat hippocampus in serum-free medium. β-Amyloid 22-35 TFA forms aggregates and typical amyloid fibrils resembling those of the β-amyloid protein in neutral buffer solution).

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β-Amyloid (22-35) (TFA) Chemical Structure

β-Amyloid (22-35) (TFA) Chemical Structure

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Description

β-Amyloid 22-35 (Amyloid β-Protein 22-35) TFA, the residues 22-35 fragment ofβ-amyloid protein, has a cytotoxic effect on cultured neurons from the rat hippocampus in serum-free medium. β-Amyloid 22-35 TFA forms aggregates and typical amyloid fibrils resembling those of the β-amyloid protein in neutral buffer solution)[1].

In Vitro

β-Amyloid 22-35 (Amyloid β-Protein 22-35) TFA shows significant cytotoxicity on the rat hippocampal neurons at 40 μg/mL, but exhibits no cytotoxic effect on the glial cells[1].

Molecular Weight

1517.64

Formula

C₆₁H₁₀₃F₃N₁₆O₂₃S

Sequence

Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met

Sequence Shortening

EDVGSNKGAIIGLM

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

β-Amyloid (22-35) (TFA)Amyloid β-Protein (22-35) (TFA)Amyloid-ββ-amyloid peptideAbetaβ-amyloidcytotoxicneuronsrathippocampusaggregatesamyloidfibrilsInhibitorinhibitorinhibit

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β-Amyloid (22-35) (TFA)
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