1-Stearoyl-2-15(S)-Hpete-Sn-Glycero-3-Pe (Synonyms: 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-phosphoethanolamine; 15(S)-HpETE-SAPE; 15(S)-hydroperoxyeicostetraenoic acid-SAPE)

Cat. No.: HY-115701: Data Sheet
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1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-Pe is a phospholipid that contains stearic acid (HY-B2219) at the sn-1 position and 15(S)-HpETE at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-Pe (SAPE) by 15-lipoxygenase (15-LO). 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-Pe (0.6 and 0.9 μM) increases ferroptotic cell death in wild-type and Acsl4 knockout Pfa1 mouse embryonic fibroblasts (MEFs) treated with the GPX4 inhibitor RSL3.

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1-Stearoyl-2-15(S)-Hpete-Sn-Glycero-3-Pe 화학구조

CAS No. : 154436-49-4

사이즈	가격	재고
Solvent
50 μg (624.96 μM * 100 μL in Ethanol)		Ask For Quote & Lead Time
Solvent
100 μg (624.96 μM * 200 μL in Ethanol)		Ask For Quote & Lead Time

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고객리뷰

제품 설명	1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-Pe is a phospholipid that contains stearic acid (HY-B2219) at the sn-1 position and 15(S)-HpETE at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-Pe (SAPE) by 15-lipoxygenase (15-LO). 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-Pe (0.6 and 0.9 μM) increases ferroptotic cell death in wild-type and Acsl4 knockout Pfa1 mouse embryonic fibroblasts (MEFs) treated with the GPX4 inhibitor RSL3.
분자량	800.05
화학식	C₄₃H₇₈NO₁₀P
CAS No.	154436-49-4
Appearance	Liquid
Color	Colorless to light yellow
SMILES	O=C(CCC/C=C\C/C=C\C/C=C\C=C\[C@@H](OO)CCCCC)O[C@H](COC(CCCCCCCCCCCCCCCCC)=O)COP(OCCN)(O)=O
선적	Shipping with dry ice.
보관	-80°C
순도&문서	Purity: 95.1% Select Batch: Data Sheet (261 KB) SDS (393 KB) COA (240 KB) Handling Instructions (2659 KB)
References	[1]. Kagan, et al. Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis. Nat. Chem. Biol. 13(1), 81-90 (2017).

1-Stearoyl-2-15(S)-Hpete-Sn-Glycero-3-Pe Related Classifications

Inflammation/Immunology

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

1-Stearoyl-2-15(S)-Hpete-Sn-Glycero-3-Pe154436-49-41-Stearoyl-2-15(S)-HpETE-sn-glycero-3-phosphoethanolamine 15(S)-HpETE-SAPE 15(S)-hydroperoxyeicostetraenoic acid-SAPEFerroptosisInhibitorinhibitorinhibit

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1-Stearoyl-2-15(S)-Hpete-Sn-Glycero-3-Pe (Synonyms: 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-phosphoethanolamine; 15(S)-HpETE-SAPE; 15(S)-hydroperoxyeicostetraenoic acid-SAPE)

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1-Stearoyl-2-15(S)-Hpete-Sn-Glycero-3-Pe Related Classifications

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