2,5-Dimethyl-1,4-benzoquinone (Synonyms: DMBQ; 2,5-Dimethyl-p-quinone; Phlorone)

Art. -Nr.: HY-W090317 Reinheit: 99.35%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

2,5-Dimethyl-1,4-benzoquinone is a jack bean urease (HY-P2767) inhibitor (IC₅₀: 0.98 μM). 2,5-Dimethyl-1,4-benzoquinone can be used in the study of soil urease activity in agriculture.

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2,5-Dimethyl-1,4-benzoquinone Chemische Struktur

CAS. Nr. : 137-18-8

Größe	Verfügbarkeit	Menge
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	Auf Lager	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	Auf Lager	Estimated Time of Arrival: December 31
Solid
500 mg	Auf Lager	Estimated Time of Arrival: December 31
1 g	Auf Lager	Estimated Time of Arrival: December 31
5 g	Auf Lager	Estimated Time of Arrival: December 31
10 g	Auf Lager	Estimated Time of Arrival: December 31
25 g	Auf Lager	Estimated Time of Arrival: December 31
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Spezialitätsempfehlungen

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biologische Aktivität
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Beschreibung

2,5-Dimethyl-1,4-benzoquinone is a jack bean urease (HY-P2767) inhibitor (IC₅₀: 0.98 μM). 2,5-Dimethyl-1,4-benzoquinone can be used in the study of soil urease activity in agriculture^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HL-60	IC₅₀	0.64 μM Compound: 2,5-dimethyl-p-benzoquinone	Antiproliferative activity against human HL60 cells Antiproliferative activity against human HL60 cells	[PMID: 18052030]
K562	IC₅₀	0.75 μM Compound: 3	In vitro cytotoxicity against Human Chronic Leukemia K562 cells In vitro cytotoxicity against Human Chronic Leukemia K562 cells	[PMID: 8558523]

Molekulargewicht

136.15

Formel

C₈H₈O₂

CAS. Nr.

137-18-8

Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1C(C)=CC(C(C)=C1)=O

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Store at room temperature 3 years

In solvent	-80°C	2 years
	-20°C	1 year

Lösungsmittel & Löslichkeit

In Vitro:

DMSO : 50 mg/mL (367.24 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	7.3448 mL	36.7242 mL	73.4484 mL
5 mM	1.4690 mL	7.3448 mL	14.6897 mL
10 mM	0.7345 mL	3.6724 mL	7.3448 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Molaritätsrechner
Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Reinheit & Dokumentation

Purity: 99.35%

Select Batch:

Data Sheet (268 KB) SDS (480 KB)

COA (247 KB) HNMR (109 KB) RP-HPLC (87 KB)

Handling Instructions (2659 KB)

Verweise

[1]. Zaborska W, et al. Inhibition of jack bean urease by 1,4-benzoquinone and 2,5-dimethyl-1,4-benzoquinone. Evaluation of the inhibition mechanism. J Enzyme Inhib Med Chem. 2002 Aug;17(4):247-53. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	7.3448 mL	36.7242 mL	73.4484 mL	183.6210 mL
	5 mM	1.4690 mL	7.3448 mL	14.6897 mL	36.7242 mL
	10 mM	0.7345 mL	3.6724 mL	7.3448 mL	18.3621 mL
	15 mM	0.4897 mL	2.4483 mL	4.8966 mL	12.2414 mL
	20 mM	0.3672 mL	1.8362 mL	3.6724 mL	9.1811 mL
	25 mM	0.2938 mL	1.4690 mL	2.9379 mL	7.3448 mL
	30 mM	0.2448 mL	1.2241 mL	2.4483 mL	6.1207 mL
	40 mM	0.1836 mL	0.9181 mL	1.8362 mL	4.5905 mL
	50 mM	0.1469 mL	0.7345 mL	1.4690 mL	3.6724 mL
	60 mM	0.1224 mL	0.6121 mL	1.2241 mL	3.0604 mL
	80 mM	0.0918 mL	0.4591 mL	0.9181 mL	2.2953 mL
	100 mM	0.0734 mL	0.3672 mL	0.7345 mL	1.8362 mL

2,5-Dimethyl-1,4-benzoquinone Related Classifications

Others

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2,5-Dimethyl-1,4-benzoquinone137-18-8DMBQ 2,5-Dimethyl-p-quinone PhloroneUreaseJack Bean UreasesoilagricultureInhibitorinhibitorinhibit

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2,5-Dimethyl-1,4-benzoquinone (Synonyms: DMBQ; 2,5-Dimethyl-p-quinone; Phlorone)

2,5-Dimethyl-1,4-benzoquinone Related Antibodies

Spezialitätsempfehlungen

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biologische Aktivität

Reinheit & Dokumentation

Verweise

Kundenbewertung

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