2-(Chloromethyl)-3,4-dimethoxypyridine hydrochloride

Name: 2-(Chloromethyl)-3,4-dimethoxypyridine hydrochloride
Brand: MedChemExpress
SKU: HY-W013510
Rating: 4.5 (0 reviews)

Cat. No.: HY-W013510 Purity: 99.70%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

2-(Chloromethyl)-3,4-dimethoxypyridine hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

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2-(Chloromethyl)-3,4-dimethoxypyridine hydrochloride 화학구조

CAS No. : 72830-09-2

사이즈	재고	수량

무료 샘플 (0.1 - 0.2 mg)	지금 신청하기
무료 샘플 (0.1 - 0.2 mg)	지금 신청하기
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	해외재고보유	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	해외재고보유	Estimated Time of Arrival: December 31
Solid
25 g	해외재고보유	Estimated Time of Arrival: December 31
50 g	해외재고보유	Estimated Time of Arrival: December 31
100 g	해외재고보유	Estimated Time of Arrival: December 31
500 g	해외재고보유	Estimated Time of Arrival: December 31
1 kg	해외재고보유	Estimated Time of Arrival: December 31

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

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Biological Activity
순도&문서
고객리뷰

제품 설명

2-(Chloromethyl)-3,4-dimethoxypyridine hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

분자량

224.08

화학식

C₈H₁₁Cl₂NO₂

CAS No.

72830-09-2

Appearance

Solid

Color

White to off-white

SMILES

COC1=CC=NC(CCl)=C1OC.Cl

선적

Room temperature in continental US; may vary elsewhere.

보관

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

용액&용해도

In Vitro:

DMSO : 13.33 mg/mL (59.49 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.4627 mL	22.3135 mL	44.6269 mL
5 mM	0.8925 mL	4.4627 mL	8.9254 mL
10 mM	0.4463 mL	2.2313 mL	4.4627 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 1.33 mg/mL (5.94 mM); Clear solution

This protocol yields a clear solution of ≥ 1.33 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (13.3 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 1.33 mg/mL (5.94 mM); Clear solution

This protocol yields a clear solution of ≥ 1.33 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (13.3 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

순도&문서

Purity: 99.70%

Select Batch:

Data Sheet (244 KB) SDS (923 KB)

COA (250 KB) HNMR (116 KB) RP-HPLC (251 KB) LCMS (229 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.4627 mL	22.3135 mL	44.6269 mL	111.5673 mL
	5 mM	0.8925 mL	4.4627 mL	8.9254 mL	22.3135 mL
	10 mM	0.4463 mL	2.2313 mL	4.4627 mL	11.1567 mL
	15 mM	0.2975 mL	1.4876 mL	2.9751 mL	7.4378 mL
	20 mM	0.2231 mL	1.1157 mL	2.2313 mL	5.5784 mL
	25 mM	0.1785 mL	0.8925 mL	1.7851 mL	4.4627 mL
	30 mM	0.1488 mL	0.7438 mL	1.4876 mL	3.7189 mL
	40 mM	0.1116 mL	0.5578 mL	1.1157 mL	2.7892 mL
	50 mM	0.0893 mL	0.4463 mL	0.8925 mL	2.2313 mL