2. Antibody-drug Conjugate/ADC Related
  3. Drug-Linker Conjugates for ADC
  4. 2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-(5-Cl)-Exatecan

2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-(5-Cl)-Exatecan 

Cat. No.: HY-171176 Purity: 99.39%
COA
SDS
Handling Instructions Technical Support

2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-(5-Cl)-Exatecan is a drug-linker conjugate for ADC. 2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-(5-Cl)-Exatecan is composed of linker and Exatecan (HY-13631).

For research use only. We do not sell to patients.

2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-(5-Cl)-Exatecan

2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-(5-Cl)-Exatecan Chemical Structure

CAS No. : 2813269-48-4

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2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-(5-Cl)-Exatecan Related Antibodies

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Description

2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-(5-Cl)-Exatecan is a drug-linker conjugate for ADC. 2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-(5-Cl)-Exatecan is composed of linker and Exatecan (HY-13631).

Molecular Weight

1107.58

Formula

C53H55ClN10O13S
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

CS(C1=NC=C(C=N1)C#CCCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCOCC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(Cl)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O)=O)(=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (90.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9029 mL 4.5143 mL 9.0287 mL
5 mM 0.1806 mL 0.9029 mL 1.8057 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.9029 mL 4.5143 mL 9.0287 mL 22.5717 mL
5 mM 0.1806 mL 0.9029 mL 1.8057 mL 4.5143 mL
10 mM 0.0903 mL 0.4514 mL 0.9029 mL 2.2572 mL
15 mM 0.0602 mL 0.3010 mL 0.6019 mL 1.5048 mL
20 mM 0.0451 mL 0.2257 mL 0.4514 mL 1.1286 mL
25 mM 0.0361 mL 0.1806 mL 0.3611 mL 0.9029 mL
30 mM 0.0301 mL 0.1505 mL 0.3010 mL 0.7524 mL
40 mM 0.0226 mL 0.1129 mL 0.2257 mL 0.5643 mL
50 mM 0.0181 mL 0.0903 mL 0.1806 mL 0.4514 mL
60 mM 0.0150 mL 0.0752 mL 0.1505 mL 0.3762 mL
80 mM 0.0113 mL 0.0564 mL 0.1129 mL 0.2821 mL
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2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-(5-Cl)-Exatecan Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-(5-Cl)-Exatecan2813269-48-4Drug-Linker Conjugates for ADCInhibitorinhibitorinhibit

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