2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-(5-Cl)-Exatecan

Art. -Nr.: HY-171176 Reinheit: 99.39%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-(5-Cl)-Exatecan is a drug-linker conjugate for ADC. 2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-(5-Cl)-Exatecan is composed of linker and Exatecan (HY-13631).

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2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-(5-Cl)-Exatecan Chemische Struktur

CAS. Nr. : 2813269-48-4

Größe	Verfügbarkeit	Menge
1 mg	Auf Lager	Estimated Time of Arrival: December 31
5 mg	Auf Lager	Estimated Time of Arrival: December 31
10 mg	Auf Lager	Estimated Time of Arrival: December 31
50 mg	Angebot einholen
100 mg	Angebot einholen

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This product is a controlled substance and not for sale in your territory.

Spezialitätsempfehlungen

•Related Small Molecules:

•Related Proteins:

Alle Drug-Linker Conjugates for ADC Isoform-spezifische Produkte anzeigen:

Alle Isoformen anzeigen

Auristatin Camptothecins Daunorubicins/Doxorubicins Duocarmycins Maytansinoids Pyrrolobenzodiazepines Traditional Cytotoxic Agents Dual payloads

Biologische Aktivität
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Beschreibung

2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-(5-Cl)-Exatecan is a drug-linker conjugate for ADC. 2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-(5-Cl)-Exatecan is composed of linker and Exatecan (HY-13631).

Molekulargewicht

1107.58

Formel

C₅₃H₅₅ClN₁₀O₁₃S

CAS. Nr.

2813269-48-4

Appearance

Solid

Color

White to light yellow

SMILES

CS(C1=NC=C(C=N1)C#CCCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCOCC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(Cl)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O)=O)(=O)=O

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Lösungsmittel & Löslichkeit

In Vitro:

DMSO : 100 mg/mL (90.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.9029 mL	4.5143 mL	9.0287 mL
5 mM	0.1806 mL	0.9029 mL	1.8057 mL
10 mM	0.0903 mL	0.4514 mL	0.9029 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molaritätsrechner
Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

Reinheit & Dokumentation

Purity: 99.39%

Select Batch:

Data Sheet (245 KB) SDS (252 KB)

COA (254 KB) HNMR (447 KB) RP-HPLC (227 KB) LCMS (96 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	0.9029 mL	4.5143 mL	9.0287 mL	22.5717 mL
	5 mM	0.1806 mL	0.9029 mL	1.8057 mL	4.5143 mL
	10 mM	0.0903 mL	0.4514 mL	0.9029 mL	2.2572 mL
	15 mM	0.0602 mL	0.3010 mL	0.6019 mL	1.5048 mL
	20 mM	0.0451 mL	0.2257 mL	0.4514 mL	1.1286 mL
	25 mM	0.0361 mL	0.1806 mL	0.3611 mL	0.9029 mL
	30 mM	0.0301 mL	0.1505 mL	0.3010 mL	0.7524 mL
	40 mM	0.0226 mL	0.1129 mL	0.2257 mL	0.5643 mL
	50 mM	0.0181 mL	0.0903 mL	0.1806 mL	0.4514 mL
	60 mM	0.0150 mL	0.0752 mL	0.1505 mL	0.3762 mL
	80 mM	0.0113 mL	0.0564 mL	0.1129 mL	0.2821 mL