3,5-Dichloropyridine

Art. -Nr.: HY-W015627 Reinheit: 99.97%: Data Sheet
COA

SDS
Handling Instructions
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3,5-dichloropyridine is a drug intermediate that can be used to synthesize metal-organic framework (MOF) materials and P2X7 receptor antagonists.

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3,5-Dichloropyridine Chemische Struktur

CAS. Nr. : 2457-47-8

Größe	Verfügbarkeit	Menge
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	Auf Lager	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	Auf Lager	Estimated Time of Arrival: December 31
Solid
25 g	Auf Lager	Estimated Time of Arrival: December 31
50 g	Auf Lager	Estimated Time of Arrival: December 31
100 g	Auf Lager	Estimated Time of Arrival: December 31
250 g	Auf Lager	Estimated Time of Arrival: December 31
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Spezialitätsempfehlungen

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biologische Aktivität
Reinheit & Dokumentation
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Beschreibung

3,5-dichloropyridine is a drug intermediate that can be used to synthesize metal-organic framework (MOF) materials and P2X7 receptor antagonists^[1]^[2].

Molekulargewicht

147.99

Formel

C₅H₃Cl₂N

CAS. Nr.

2457-47-8

Appearance

Solid

Color

White to off-white

SMILES

C1=C(Cl)C=NC=C1Cl

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Lösungsmittel & Löslichkeit

In Vitro:

DMSO : 100 mg/mL (675.72 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.7572 mL	33.7861 mL	67.5721 mL
5 mM	1.3514 mL	6.7572 mL	13.5144 mL
10 mM	0.6757 mL	3.3786 mL	6.7572 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molaritätsrechner
Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

Reinheit & Dokumentation

Purity: 99.97%

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Data Sheet (270 KB) SDS (614 KB)

COA (247 KB) HNMR (108 KB) GC (203 KB)

Handling Instructions (2659 KB)

Verweise

[1]. Etaiw Sel-D, El-bendary MM. Structure and applications of metal-organic framework based on cyanide and 3,5-dichloropyridine. Spectrochim Acta A Mol Biomol Spectrosc. 2013 Jun;110:304-10. [Content Brief]

[2]. Lee WG, et al. Structure-activity relationships and optimization of 3,5-dichloropyridine derivatives as novel P2X(7) receptor antagonists. J Med Chem. 2012 Apr 26;55(8):3687-98. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	6.7572 mL	33.7861 mL	67.5721 mL	168.9303 mL
	5 mM	1.3514 mL	6.7572 mL	13.5144 mL	33.7861 mL
	10 mM	0.6757 mL	3.3786 mL	6.7572 mL	16.8930 mL
	15 mM	0.4505 mL	2.2524 mL	4.5048 mL	11.2620 mL
	20 mM	0.3379 mL	1.6893 mL	3.3786 mL	8.4465 mL
	25 mM	0.2703 mL	1.3514 mL	2.7029 mL	6.7572 mL
	30 mM	0.2252 mL	1.1262 mL	2.2524 mL	5.6310 mL
	40 mM	0.1689 mL	0.8447 mL	1.6893 mL	4.2233 mL
	50 mM	0.1351 mL	0.6757 mL	1.3514 mL	3.3786 mL
	60 mM	0.1126 mL	0.5631 mL	1.1262 mL	2.8155 mL
	80 mM	0.0845 mL	0.4223 mL	0.8447 mL	2.1116 mL
	100 mM	0.0676 mL	0.3379 mL	0.6757 mL	1.6893 mL