3-Methoxytyramine (hydrochloride)
Based on 7 publication(s) in Google Scholar
3-Methoxytyramine hydrochloride is an metabolite of dopamine which can activate trace amine associated receptor 1 (TAAR1).
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98.23%
- CAS 番号: 1477-68-5
- 分子式: C9H14ClNO2
- 分子量:203.67
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保管条件:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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HY-103638A
3-MethoxytyramineDopamine Inactive Metabolite -
HY-113468
3-O-Methyl-DL-DOPAEndogenous Metabolite -
HY-103638R
3-Methoxytyramine hydrochloride (Standard)Dopamine Inactive Metabolite -
HY-100599
Urolithin AMitophagy Activator -
HY-B0451A
Dopamine hydrochlorideCatecholamine Neurotransmitter -
HY-B0451AR
Dopamine hydrochloride (Standard)Catecholamine Neurotransmitter -
HY-I0736
Isonicotinic acidPyridine carboxylic acid -
HY-113468R
3-O-Methyl-DL-DOPA (Standard)Endogenous Metabolite -
HY-103638AR
3-Methoxytyramine (Standard)Dopamine Inactive Metabolite -
HY-101022
CXCR2-IN-1CXCR2 Antagonist -
HY-116016A
Etilevodopa hydrochlorideLevodopa Prodrug -
HY-I0736R
Isonicotinic acid (Standard)Standard Of Isonicotinic Acid
MedChemExpress（MCE）の使用を引用している文献 3-Methoxytyramine hydrochloride
More- Phytomedicine. 2025 Jul 25:143:156876. [Abstract]
- Free Radic Biol Med. 2025 Feb 1:227:434-445. [Abstract]
- Anal Chem. 2026 Jun 16;98(23):16962-16970. [Abstract]
- J Ethnopharmacol. 2026 Apr 6:360:121109. [Abstract]
- Results Chem. 2026 Apr 21;26:103342.
- Algal Res. 2026 Jun 18;97:104799.
- bioRxiv. 2026 May 6.
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
IC50 & Target
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Human Endogenous Metabolite |
体外実験
The intensity of the fluorescence developed is in a linear relation to the amount of 3-Methoxytyramine hydrochloride presented in the sample up to at least 1 μg. When a high concentration of dopamine is present in the reaction mixture, there is some reduction in the fluorescence derived from 3-Methoxytyramine hydrochloride[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
体内実験
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1477-68-5
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性状 Solid
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分子量 203.67
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分子式 C9H14ClNO2
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Color Off-white to light brown
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SMILES
COC1=C(O)C=CC(CCN)=C1.Cl
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別名
3-O-methyl Dopamine (hydrochloride); 3-O-メチルドーパミン塩酸塩
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (7)
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Journal Impact Factor
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Most Recent
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Phytomedicine
Neuroprotective effects of Gastrodia elata and its compounds in a Caenorhabditis elegans Alzheimer's disease model. [Abstract]2025 Jul 25:143:156876. PMID: 40408941 -
Free Radic Biol Med
6‴-Feruloylspinosin alleviates Aβ-induced toxicity by modulating relevant neurotransmitter and the AMPK/mTOR signaling pathway. [Abstract]2025 Feb 1:227:434-445. PMID: 39653128 -
Anal Chem
High-Throughput Reactive Desorption Electrospray Ionization Mass Spectrometry for Targeted Derivatization and Analysis of Poorly Ionized Small Molecules. [Abstract]2026 Jun 16;98(23):16962-16970. PMID: 42223360 -
J Ethnopharmacol
Metabolomic insights into the neuroprotective actions of Ziziphi spinosae semen and jujuboside B against Aβ-induced toxicity. [Abstract]2026 Apr 6:360:121109. PMID: 41483858 -
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溶剤 & 溶解度
体外:
DMSO : ≥ 100 mg/mL (490.99 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
体内:
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (12.27 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (12.27 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
純度とドキュメンテーション
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データシート (277 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.9099 mL | 24.5495 mL | 49.0990 mL | 122.7476 mL |
| 5 mM | 0.9820 mL | 4.9099 mL | 9.8198 mL | 24.5495 mL | |
| 10 mM | 0.4910 mL | 2.4550 mL | 4.9099 mL | 12.2748 mL | |
| 15 mM | 0.3273 mL | 1.6366 mL | 3.2733 mL | 8.1832 mL | |
| 20 mM | 0.2455 mL | 1.2275 mL | 2.4550 mL | 6.1374 mL | |
| 25 mM | 0.1964 mL | 0.9820 mL | 1.9640 mL | 4.9099 mL | |
| 30 mM | 0.1637 mL | 0.8183 mL | 1.6366 mL | 4.0916 mL | |
| 40 mM | 0.1227 mL | 0.6137 mL | 1.2275 mL | 3.0687 mL | |
| 50 mM | 0.0982 mL | 0.4910 mL | 0.9820 mL | 2.4550 mL | |
| 60 mM | 0.0818 mL | 0.4092 mL | 0.8183 mL | 2.0458 mL | |
| 80 mM | 0.0614 mL | 0.3069 mL | 0.6137 mL | 1.5343 mL | |
| 100 mM | 0.0491 mL | 0.2455 mL | 0.4910 mL | 1.2275 mL |
3-Methoxytyramine hydrochloride 関連分類
HY-103638 関連分類
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