4-(4-chlorophenyl)thiazol-2-amine

Cat. No.: HY-W052190 Purity: 99.84%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

4-(4-chlorophenyl)thiazol-2-amine (Compound A) is the derivative of Aminothiazole (HY-12396).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

4-(4-chlorophenyl)thiazol-2-amine 화학구조

CAS No. : 2103-99-3

사이즈	재고	수량

무료 샘플 (0.1 - 0.2 mg)	지금 신청하기
무료 샘플 (0.1 - 0.2 mg)	지금 신청하기
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	해외재고보유	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	해외재고보유	Estimated Time of Arrival: December 31
Solid
1 g	해외재고보유	Estimated Time of Arrival: December 31
5 g	해외재고보유	Estimated Time of Arrival: December 31
10 g	해외재고보유	Estimated Time of Arrival: December 31
25 g	해외재고보유	Estimated Time of Arrival: December 31
50 g	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

4-(4-chlorophenyl)thiazol-2-amine (Compound A) is the derivative of Aminothiazole (HY-12396)^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HUVEC	IC₅₀	> 10 μM Compound: 22	Antiangiogenic activity against human HUVEC cells assessed as inhibition of [3H]thymidine incorporation incubated for 24 hrs prior to [3H]thymidine addition measured after 6 hrs by microbeta counting analysis Antiangiogenic activity against human HUVEC cells assessed as inhibition of [3H]thymidine incorporation incubated for 24 hrs prior to [3H]thymidine addition measured after 6 hrs by microbeta counting analysis	[PMID: 23518276]

분자량

210.69

화학식

C₉H₇ClN₂S

CAS No.

2103-99-3

Appearance

Solid

Color

Off-white to light yellow

SMILES

ClC1=CC=C(C2=CSC(N)=N2)C=C1

선적

Room temperature in continental US; may vary elsewhere.

보관

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

용액&용해도

In Vitro:

DMSO : ≥ 200 mg/mL (949.27 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.7463 mL	23.7317 mL	47.4633 mL
5 mM	0.9493 mL	4.7463 mL	9.4927 mL
10 mM	0.4746 mL	2.3732 mL	4.7463 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: 99.84%

Select Batch:

Data Sheet (268 KB) SDS (480 KB)

COA (247 KB) HNMR (114 KB) RP-HPLC (185 KB)

Handling Instructions (2659 KB)

References

[1]. Caba-Flores MD, et al., Activity In Vitro of 2-Chloro-N-[4-(4-Chlorophenyl)-2-Thiazolyl]Acetamide Against Promastigotes of Leishmania mexicana: An Apoptosis Inducer. Acta Parasitol. 2021 Sep;66(3):1068-1073. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.7463 mL	23.7317 mL	47.4633 mL	118.6583 mL
	5 mM	0.9493 mL	4.7463 mL	9.4927 mL	23.7317 mL
	10 mM	0.4746 mL	2.3732 mL	4.7463 mL	11.8658 mL
	15 mM	0.3164 mL	1.5821 mL	3.1642 mL	7.9106 mL
	20 mM	0.2373 mL	1.1866 mL	2.3732 mL	5.9329 mL
	25 mM	0.1899 mL	0.9493 mL	1.8985 mL	4.7463 mL
	30 mM	0.1582 mL	0.7911 mL	1.5821 mL	3.9553 mL
	40 mM	0.1187 mL	0.5933 mL	1.1866 mL	2.9665 mL
	50 mM	0.0949 mL	0.4746 mL	0.9493 mL	2.3732 mL
	60 mM	0.0791 mL	0.3955 mL	0.7911 mL	1.9776 mL
	80 mM	0.0593 mL	0.2966 mL	0.5933 mL	1.4832 mL
	100 mM	0.0475 mL	0.2373 mL	0.4746 mL	1.1866 mL