2. Anti-infection
  3. Bacterial Fungal Virus Protease
  4. Aminothiazole

Aminothiazole  (Synonyms: 2-Aminothiazole; 2-Thiazolylamine)

Cat. No.: HY-12396 Purity: ≥98.0%
COA Handling Instructions

Molarity Calculator

Aminothiazole (2-Aminothiazole), a typical heterocyclic amine, is a precursor for the synthesis of biologically active molecules including sulfur agents, biocides, fungicides, antibiotics, dyes and chemical reaction accelerators.

For research use only. We do not sell to patients.

Aminothiazole Chemical Structure

Aminothiazole Chemical Structure

CAS No. : 96-50-4

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10 mM * 1 mL in DMSO
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Based on 1 publication(s) in Google Scholar

Aminothiazole Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Aminothiazole

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Aminothiazole (2-Aminothiazole), a typical heterocyclic amine, is a precursor for the synthesis of biologically active molecules including sulfur agents, biocides, fungicides, antibiotics, dyes and chemical reaction accelerators[1][2].

In Vitro

Aminothiazole can be used as a thyroid inhibitor in the research of hyperthyroidism and it has antibacterial activity[1].
Aminothiazole can be used for the synthesis of antitubercular and antibacterial agents[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Aminothiazole Related Antibodies
Molecular Weight

100.14

Formula

C3H4N2S
CAS No.
Appearance

Solid

Color

Off-white to yellow

SMILES

NC1=NC=CS1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (998.60 mM)

DMSO : ≥ 50 mg/mL (499.30 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 9.9860 mL 49.9301 mL 99.8602 mL
5 mM 1.9972 mL 9.9860 mL 19.9720 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.5 mg/mL (24.97 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

    Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
  • Protocol 2

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 2.5 mg/mL (24.97 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

    Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.16%

COA (249 KB) HNMR (117 KB) GC (98 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 9.9860 mL 49.9301 mL 99.8602 mL 249.6505 mL
5 mM 1.9972 mL 9.9860 mL 19.9720 mL 49.9301 mL
10 mM 0.9986 mL 4.9930 mL 9.9860 mL 24.9650 mL
15 mM 0.6657 mL 3.3287 mL 6.6573 mL 16.6434 mL
20 mM 0.4993 mL 2.4965 mL 4.9930 mL 12.4825 mL
25 mM 0.3994 mL 1.9972 mL 3.9944 mL 9.9860 mL
30 mM 0.3329 mL 1.6643 mL 3.3287 mL 8.3217 mL
40 mM 0.2497 mL 1.2483 mL 2.4965 mL 6.2413 mL
50 mM 0.1997 mL 0.9986 mL 1.9972 mL 4.9930 mL
60 mM 0.1664 mL 0.8322 mL 1.6643 mL 4.1608 mL
80 mM 0.1248 mL 0.6241 mL 1.2483 mL 3.1206 mL
100 mM 0.0999 mL 0.4993 mL 0.9986 mL 2.4965 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Aminothiazole Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Aminothiazole96-50-42-Aminothiazole 2-ThiazolylamineBacterialFungalVirus ProteasesulfurbiocidesfungicidesantibioticsdyesInhibitorinhibitorinhibit

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