2. Disease Areas
  3. Metabolic or Endocrine Disease
  4. Thyroid Disease
  5. Hyperthyroidism

Hyperthyroidism

Hyperthyroidism is an endocrine disorder characterized by the overproduction and release of thyroid hormones by the thyroid gland, leading to thyrotoxicosis and a wide range of systemic effects. Common symptoms include nervousness, irritability, weight loss, heat intolerance, palpitations, tremors, fatigue, muscle weakness, insomnia, and changes in menstrual cycles. In severe cases, it can progress to thyroid storm, a life-threatening condition. The most frequent cause is Graves' disease, an autoimmune disorder, though other causes include toxic multinodular goiter and thyroiditis. Left untreated, hyperthyroidism can lead to serious complications such as atrial fibrillation, heart failure, osteoporosis, and infertility. Treatment options include antithyroid medications, radioactive iodine therapy, and surgery, with the goal of normalizing hormone levels and alleviating symptoms.

Hyperthyroidism (1):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-180503
    19-Nor-22-oxa-1a,25(OH)2-VD3 284041-36-7
    19-Nor-22-oxa-1a,25(OH)2-VD3 is a vitamin D₃ analogue. 19-Nor-22-oxa-1a,25(OH)2-VD3 has an extremely low affinity for the vitamin D receptor (VDR) and hardly binds to the vitamin D binding protein (DBP). 19-Nor-22-oxa-1a,25(OH)2-VD3 can effectively induce the differentiation of HL-60 cells and cause G₀-G₁ phase cell cycle arrest. 19-Nor-22-oxa-1a,25(OH)2-VD3 can be used to study diseases such as excessive hyperparathyroidism.
    19-Nor-22-oxa-1a,25(OH)2-VD3