5-Bromo-1,3-benzodioxole

Name: 5-Bromo-1,3-benzodioxole
Brand: MedChemExpress
SKU: HY-75212
Rating: 4.5 (0 reviews)

Cat. No.: HY-75212 Purity: 99.95%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

5-Bromo-1,3-benzodioxole is an organic compound that serves as an important intermediate in the synthesis of Piperonyl Butoxide-UL-Phenyl-'C.

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5-Bromo-1,3-benzodioxole 화학구조

CAS No. : 2635-13-4

사이즈	재고	수량
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	해외재고보유	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	해외재고보유	Estimated Time of Arrival: December 31
Liquid
100 g	해외재고보유	Estimated Time of Arrival: December 31
500 g	해외재고보유	Estimated Time of Arrival: December 31
> 100 g	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

5-Bromo-1,3-benzodioxole is an organic compound that serves as an important intermediate in the synthesis of Piperonyl Butoxide-UL-Phenyl-'C^[1].

In Vitro

5-Bromo-1,3-benzodioxole is a precursor to Piperonyl Butoxide, which acts as a synergist to enhance the effectiveness of pesticides^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

201.02

화학식

C₇H₅BrO₂

CAS No.

2635-13-4

Appearance

Liquid (Density: 1.669 g/cm³)

Color

Colorless to light yellow

SMILES

BrC1=CC=C(OCO2)C2=C1

선적

Room temperature in continental US; may vary elsewhere.

보관

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

용액&용해도

In Vitro:

DMSO : 100 mg/mL (497.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.9747 mL	24.8733 mL	49.7465 mL
5 mM	0.9949 mL	4.9747 mL	9.9493 mL
10 mM	0.4975 mL	2.4873 mL	4.9747 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (12.44 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 2

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (12.44 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

순도&문서

Purity: 99.95%

Select Batch:

Data Sheet (273 KB) SDS (393 KB)

COA (250 KB) HNMR (116 KB) GC (178 KB)

Handling Instructions (2659 KB)

References

[1]. J.E. Immoos, A.J. Brattesani, et al. SYNTHESIS OF PIPERONYL BUTOXIDE-UL-PFIENYL-'4C . Journal of Labelled Compounds and Radiopharmaceuticals-Vol. XXXVIII, No. 6.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.9747 mL	24.8733 mL	49.7465 mL	124.3664 mL
	5 mM	0.9949 mL	4.9747 mL	9.9493 mL	24.8733 mL
	10 mM	0.4975 mL	2.4873 mL	4.9747 mL	12.4366 mL
	15 mM	0.3316 mL	1.6582 mL	3.3164 mL	8.2911 mL
	20 mM	0.2487 mL	1.2437 mL	2.4873 mL	6.2183 mL
	25 mM	0.1990 mL	0.9949 mL	1.9899 mL	4.9747 mL
	30 mM	0.1658 mL	0.8291 mL	1.6582 mL	4.1455 mL
	40 mM	0.1244 mL	0.6218 mL	1.2437 mL	3.1092 mL
	50 mM	0.0995 mL	0.4975 mL	0.9949 mL	2.4873 mL
	60 mM	0.0829 mL	0.4146 mL	0.8291 mL	2.0728 mL
	80 mM	0.0622 mL	0.3109 mL	0.6218 mL	1.5546 mL
	100 mM	0.0497 mL	0.2487 mL	0.4975 mL	1.2437 mL