2. GPCR/G Protein
  3. Endothelin Receptor
  4. Atrial Natriuretic Peptide (ANP) (1-28), rat, mouse TFA

Atrial Natriuretic Peptide (ANP) (1-28), rat, mouse TFA  (Synonyms: Atrial natriuretic factor (1-28) (rat, mouse) TFA)

Cat. No.: HY-P1236A Pureza: 99.32%
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Atrial Natriuretic Peptide (ANP) (1-28), rat, mouse (TFA) is a major circulating form of ANP in rats, potently inhibits Angiotensin II (Ang II)-stimulated endothelin-1 secretion in a concentration-dependent manner.

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Atrial Natriuretic Peptide (ANP) (1-28), rat, mouse TFA

Atrial Natriuretic Peptide (ANP) (1-28), rat, mouse TFA Estructura química

Tamaño Precio Stock Cantidad
500 μg En stock
1 mg En stock
5 mg Obtener un presupuesto
10 mg   Obtener un presupuesto  
50 mg   Obtener un presupuesto  

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Based on 1 Customer Validation

Other Forms of Atrial Natriuretic Peptide (ANP) (1-28), rat, mouse TFA:

Atrial Natriuretic Peptide (ANP) (1-28), rat, mouse TFA Related Antibodies

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Descripciòn

Atrial Natriuretic Peptide (ANP) (1-28), rat, mouse (TFA) is a major circulating form of ANP in rats, potently inhibits Angiotensin II (Ang II)-stimulated endothelin-1 secretion in a concentration-dependent manner.

IC50 & Target

Endothelin-1[1]
In Vitro

Rat ANP (1-28) and rat BNP-45, which are the respective major circulating forms of ANP and BNP in rats, potently inhibited Ang II-stimulated endothelin-1 secretion in a concentration-dependent manner. Rat ANP (5-25) is less effective that Rat ANP(1-28) with respect to inhibiting immunoreactive (ir)-endothelin-1 secretion and increasing cellular cyclic GMP. Rat ANP (1-28) inhibits the secretion of ir-endothelin-1 in a concentration-dependent manner between 0.01 and 1 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Atrial Natriuretic Peptide (ANP) (1-28), rat, mouse TFA Related Antibodies
Peso molecular

3176.43

Fòrmula

C130H206N45F3O41S2
Appearance

Solid

Color

White to off-white

Sequence

Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr (Disulfide bridge: Cys7-Cys23)
Sequence Shortening

SLRRSSCFGGRIDRIGAQSGLGCNSFRY (Disulfide bridge: Cys7-Cys23)
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvente y solubilidad
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
Pureza y Documentación
Referencias
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Atrial Natriuretic Peptide (ANP) (1-28), rat, mouse TFA Related Classifications

  • Calculadora de molaridad

  • Calculadora de dilución

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Atrial Natriuretic Peptide (ANP) (1-28), rat, mouseAtrial natriuretic factor (1-28) (rat, mouse)Endothelin ReceptorInhibitorinhibitorinhibit

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Nombre del producto:
Atrial Natriuretic Peptide (ANP) (1-28), rat, mouse TFA
Cat. No.:
HY-P1236A
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