1. Anti-infection
    Metabolic Enzyme/Protease
  2. HCV
    HCV Protease

Daclatasvir dihydrochloride (Synonyms: BMS-790052 dihydrochloride)

Cat. No.: HY-10465 Purity: 99.70%
Data Sheet SDS Handling Instructions

BMS-790052 is a highly selective inhibitor of HCV NS5A with EC50 of 9-50 pM, for a broad range of HCV replicon genotypes and the JFH-1 genotype 2a infectious virus in cell culture.

For research use only. We do not sell to patients.
Daclatasvir dihydrochloride Chemical Structure

Daclatasvir dihydrochloride Chemical Structure

CAS No. : 1009119-65-6

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO $67 In-stock
5 mg $50 In-stock
10 mg $75 In-stock
50 mg $150 In-stock
100 mg $190 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Other Forms of Daclatasvir dihydrochloride:

  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

BMS-790052 is a highly selective inhibitor of HCV NS5A with EC50 of 9-50 pM, for a broad range of HCV replicon genotypes and the JFH-1 genotype 2a infectious virus in cell culture. IC50 Value: 9-50 pM Target: HCV NS5A BMS-790052 has broad genotype coverage and exhibits picomolar in vitro potency against genotypes 1a (EC50 50pm) and 1b (EC50 9pm). BMS-790052 produces a robust decline in HCV RNA (-3.6 logs after 48 hours from a single 100 mg) dosefollowing a single dose in patients chronically infected with HCV genotype 1.

Clinical Trial
View MoreCollapse
References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 1.2318 mL 6.1592 mL 12.3183 mL
5 mM 0.2464 mL 1.2318 mL 2.4637 mL
10 mM 0.1232 mL 0.6159 mL 1.2318 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

811.8

Formula

C₄₀H₅₂Cl₂N₈O₆

CAS No.

1009119-65-6

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 56 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Daclatasvir dihydrochloride
Cat. No.:
HY-10465
Quantity: