1. Anti-infection
  2. Bacterial
  3. Ethacridine lactate

Ethacridine lactate (Synonyms: Acrinol)

Cat. No.: HY-B2174 Purity: 99.62%
Handling Instructions

Ethacridine lactate is a poly(ADP-ribose) glycohydrolase (PARG) inhibitor.

For research use only. We do not sell to patients.

Ethacridine lactate Chemical Structure

Ethacridine lactate Chemical Structure

CAS No. : 1837-57-6

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply Now  
10 mM * 1 mL in DMSO USD 66 In-stock
Estimated Time of Arrival: December 31
100 mg USD 60 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 2 publication(s) in Google Scholar

Other Forms of Ethacridine lactate:

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Ethacridine lactate is a poly(ADP-ribose) glycohydrolase (PARG) inhibitor.

IC50 & Target


In Vitro

Ethacridine lactate is effective against mostly gram-positive species like Streptococci and Staphylococci and ineffective against gram-negative(P seudomonas aeruginosa)[1]. Ethacridine Lactate is a safe abortifacient with about 80% success and hardly any side effects[2].

In Vivo

The incidence of retained placenta is 16%. The extra-amniotic injection is a technically simple procedure and can be carried out even between 13-15 weeks of pregnancy when intraamniotic injection is difficult. Its bactericidal properties minimize the danger of post-abortal infection. It can be used in certain medical conditions like hypertension, bronchial asthma where hypertonic saline and prostaglandin are contraindi-cated[2]. Ethacridine lactate performs better than other instillation abortion methods and it is a safe and effective method. Ethacridine lactate induces successful abortion in 92.8% of cases which is much higher than that found in the literature (about 82%). Abortion failure occurrs in the other 4 cases because of transverse lie of fetus, cervical dystocia, and uterine inertia[2].

Molecular Weight









Room temperature in continental US; may vary elsewhere.

Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (291.22 mM)

*"≥" means soluble, but saturation unknown.

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9122 mL 14.5611 mL 29.1223 mL
5 mM 0.5824 mL 2.9122 mL 5.8245 mL
10 mM 0.2912 mL 1.4561 mL 2.9122 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (7.28 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (7.28 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (7.28 mM); Clear solution

*All of the co-solvents are provided by MCE.
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2



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