1. Anti-infection
  2. Bacterial
  3. Ethacridine lactate monohydrate

Ethacridine lactate monohydrate (Synonyms: Acrinol monohydrate)

Cat. No.: HY-B0889 Purity: 99.70%
Handling Instructions

Ethacridine lactate (Acrinol) monohydrate is a widely used antiseptic and abortifacient. Ethacridine lactate monohydrate is effective against Staphylococcus aureus and other gram-positive cocci. Ethacridine lactate monohydrate is also a poly(ADP-ribose) glycohydrolase (PARG) inhibitor.

For research use only. We do not sell to patients.

Ethacridine lactate monohydrate Chemical Structure

Ethacridine lactate monohydrate Chemical Structure

CAS No. : 6402-23-9

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply Now  
Solution
10 mM * 1 mL in DMSO USD 66 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 66 In-stock
Estimated Time of Arrival: December 31
Solid
100 mg USD 60 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 2 publication(s) in Google Scholar

Other Forms of Ethacridine lactate monohydrate:

Top Publications Citing Use of Products

2 Publications Citing Use of MCE Ethacridine lactate monohydrate

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Ethacridine lactate (Acrinol) monohydrate is a widely used antiseptic and abortifacient. Ethacridine lactate monohydrate is effective against Staphylococcus aureus and other gram-positive cocci. Ethacridine lactate monohydrate is also a poly(ADP-ribose) glycohydrolase (PARG) inhibitor[1][2][3].

IC50 & Target

poly(ADP-ribose) glycohydrolase (PARG)[2]

In Vitro

Acrinol is effective against S. aureus including MRSA, with the MICs ranging from 100-200 μg/mL. The MIC of Acrinol for Eschericia coli is 200-800 μg/mL, and it is over 1,600 μg/mL for Proteus vulgaris and Proteus mirabilis[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Ethacridine lactate can be used for termination of pregnancy[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

361.39

Formula

C18H23N3O5

CAS No.
SMILES

CC(O)C(O)=O.NC1=CC2=NC3=CC=C(OCC)C=C3C(N)=C2C=C1.O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (276.71 mM)

H2O : 2 mg/mL (5.53 mM; Need ultrasonic)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7671 mL 13.8355 mL 27.6709 mL
5 mM 0.5534 mL 2.7671 mL 5.5342 mL
10 mM 0.2767 mL 1.3835 mL 2.7671 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (6.92 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (6.92 mM); Clear solution

*All of the co-solvents are available by MCE.
References
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  • Molarity Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2

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Ethacridine lactate monohydrate
Cat. No.:
HY-B0889
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