6402-23-9
6402-23-9
Chemical Structure
Ethacridine lactate monohydrate
Synonym(s): Acrinol monohydrate
- CAS No.: 6402-23-9
- Formula:C18H23N3O5
- Molecular Weight:361.39
IUPAC Name: 7-ethoxyacridine-3,9-diamine 2-hydroxypropanoate hydrate
InChIKey: NYEPHMYJRNWPLA-UHFFFAOYSA-N
SMILES: CC(O)C(O)=O.NC1=CC2=NC3=CC=C(OCC)C=C3C(N)=C2C=C1.O
Biological Activity: Ethacridine lactate (Acrinol) monohydrate is a widely used antiseptic and abortifacient. Ethacridine lactate monohydrate is effective against Staphylococcus aureus and other gram-positive cocci. Ethacridine lactate monohydrate is also a poly(ADP-ribose) glycohydrolase (PARG) inhibitor[1][2][3].
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Ethacridine lactate monohydrate | 99.85% | Ethacridine lactate (Acrinol) monohydrate is a widely used antiseptic and abortifacient. Ethacridine lactate monohydrate is effective against Staphylococcus aureus and other gram-positive cocci. Ethacridine lactate monohydrate is also a poly(ADP-ribose) glycohydrolase (PARG) inhibitor. | ||||||||||||||||||||
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Ethacridine lactate monohydrate (Standard) | ≥98% | Ethacridine (lactate monohydrate) (Standard) is the analytical standard of Ethacridine (lactate monohydrate). This product is intended for research and analytical applications. Ethacridine lactate (Acrinol) monohydrate is a widely used antiseptic and abortifacient. Ethacridine lactate monohydrate is effective against Staphylococcus aureus and other gram-positive cocci. Ethacridine lactate monohydrate is also a poly(ADP-ribose) glycohydrolase (PARG) inhibitor. | ||||||||||||||||||||
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References
- [1]. Gupta S, et, al. Ethacridine lactate -- a safe and effective drug for termination of pregnancy. Indian J Matern Child Health. 1993;4(2):59-61. [Content Brief]
- [2]. Rotin LE, et al. Erlotinib synergizes with the poly(ADP-ribose) glycohydrolase inhibitor ethacridine in acute myeloid leukemia cells. Haematologica. 2016 Nov;101(11):e449-e453. [Content Brief]
- [3]. Usuki R, et, al. Antibacterial Activity of Acrinol against Organisms Isolated from Clinical Materials and Influence of Light on Antibacterial Activity of Acrinol. Japanese Journal of Pharmaceutical Health Care and Sciences. 2004 Jan; 30(2):72-77.
