3,6-Diaminoacridine dihydrochloride
Based on 3 publication(s) in Google Scholar
3,6-Diaminoacridine dihydrochloride is a versatile acridine compound. 3,6-Diaminoacridine dihydrochloride exerts antibacterial activity by intercalating into bacterial DNA, interfering with replication and transcription, and inducing bacterial lysis. 3,6-Diaminoacridine dihydrochloride is an acridine dye and also a DNA intercalator.
For research use only. We do not sell to patients.
- CAS No.: 531-73-7
- Formula: C13H13Cl2N3
- Molecular Weight:282.17
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) 3,6-Diaminoacridine dihydrochloride
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Biological Activity
3,6-Diaminoacridine dihydrochloride induces cytotoxicity in transformed Chinese hamster ovary cells, with an IC50 of 1.1 μM[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 531-73-7
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Molecular Weight 282.17
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Formula C13H13Cl2N3
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SMILES
NC1=CC2=NC3=CC(N)=CC=C3C=C2C=C1.Cl.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (3)
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Journal Impact Factor
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Most Recent
Purity & Documentation
References
[1]. Kubota Y, et al. Fluorescence decay studies of the DNA-3,6-diaminoacridine complexes. Biophys Chem. 1984;19(1):25-37. [Content Brief]
[2]. Gamage SA, et al. Synthesis and in vitro evaluation of 9-anilino-3,6-diaminoacridines active against a multidrug-resistant strain of the malaria parasite Plasmodium falciparum. J Med Chem. 1994;37(10):1486-1494. [Content Brief]
[3]. Sabolova D, et al. Proflavine/acriflavine derivatives with versatile biological activities. J Appl Toxicol. 2020;40(1):64-71. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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