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  3. Polidocanol,Hydroxyl Value 40-60 mgKOH/g

Polidocanol,Hydroxyl Value 40-60 mgKOH/g  (Synonyms: Polyoxyethylene lauryl ether; Polyoxyethyleneglycol Dodecyl Ether)

Cat. No.: HY-B2106 Pureté: 98.0%
Instruction de manipulation Technical Support

Polidocanol is a sclerosing agent used successfully to treat extremity and esophageal varices and telangiectasias.

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Polidocanol,Hydroxyl Value 40-60 mgKOH/g

Polidocanol,Hydroxyl Value 40-60 mgKOH/g Chemical Structure

CAS No. : 9002-92-0

Size Prix Stock Quantité
500 mg En stock
1 g En stock
5 g En stock
10 g   Obtenir un devis  
50 g   Obtenir un devis  

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Description

Polidocanol is a sclerosing agent used successfully to treat extremity and esophageal varices and telangiectasias.

In Vivo

Polidocanol (0.5%, 1%, and 2%) results in significantly more adhesions than tetracycline, whereas the effect of diluted polidocanol is similar to that of tetracycline in rats. The higher concentrations of polidocanol, of 0.5%, 1%, and 2% are more effective than either the diluted polidocanol or tetracycline against pleurodesis[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Formule

(C2H4O)nC12H26O

CAS No.
Appearance

<41°C Solid,>45°C Liquid

Color

White to light yellow

SMILES

OCCCOCCCCCCCCCCCCC.[n]

Livraison

Room temperature in continental US; may vary elsewhere.

Stockage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvant et solubilité
In Vitro: 

H2O : 50 mg/mL (Need ultrasonic)

DMSO : 50 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

  • Calculateur de molarité

  • Calculateur de dilution

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 120 mg/mL; Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Pureté et documentation

Purity: 98.0%

Références
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nom du produit:
Polidocanol,Hydroxyl Value 40-60 mgKOH/g
Cat. No.:
HY-B2106
Quantité:
MCE Japan Authorized Agent: