1. Metabolic Enzyme/Protease
  2. HIF/HIF Prolyl-Hydroxylase
  3. Prolyl Hydroxylase inhibitor 1

Prolyl Hydroxylase inhibitor 1 (Compound 15i) is an orally active hypoxia inducible factor (HIF)-prolyl hydroxylase (PHD) inhibitor with an IC50 of 62.23 nM. Antianemia agent.

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Prolyl Hydroxylase inhibitor 1

Prolyl Hydroxylase inhibitor 1 Estructura química

No. CAS : 2205125-60-4

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Descripciòn

Prolyl Hydroxylase inhibitor 1 (Compound 15i) is an orally active hypoxia inducible factor (HIF)-prolyl hydroxylase (PHD) inhibitor with an IC50 of 62.23 nM[1]. Antianemia agent[1].

IC50 & Target

IC50: 62.23±2.33nM (HIF-PHD)[1]

Peso molecular

415.83

Fòrmula

C19H18ClN5O4

No. CAS
SMILES

O=C(NCC(O)=O)C1=C(O)C=C(C2=CN(CCCC3=CC=C(Cl)C=C3)N=N2)C=N1

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
Prolyl Hydroxylase inhibitor 1
Cat. No.:
HY-112441
Cantidad:
MCE Japan Authorized Agent: