2. Endocrinology

Endocrinology

Endocrinology

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Found in most species of the animal kingdom, the endocrine system consists of glands that secrete hormones, and receptors that detect and react to the hormones. In response to environmental stimuli, the endocrine system secretes hormones and uses them as chemical messengers to orchestrate physiological, developmental and reproductive changes that affect the entire body for a long period of time. In order to maintain the proper functioning of the body through its entire life cycle, the endocrine system utilizes a complex feedback mechanism to fine-tune the balance of hormones in the bloodstream. Even a slight disruption to endocrine system’s function can throw off the delicate balance of hormones in the human body and lead to an endocrine disorder, or endocrine disease, such as diabetes, adrenal insufficiency, hyper- or hypothyroidism, and polycystic ovary syndrome (PCOS).

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P3833
    Yp537 166664-90-0 98%
    Yp537 is an estrogen receptor (ER) inhibitor that blocks dimerization of the human estrogen receptor.
    Yp537
  • HY-P3835
    Mating Factor α (1-6) 65418-88-4 98%
    Mating Factor α (1-6) is a mating factor produced by α-mating type cells of Saccharomyces cerevisiae and an acts as an inhibitor of the initiation of DNA synthesis in the cells.
    Mating Factor α (1-6)
  • HY-P3903
    [D-Trp8,Tyr11] Somatostatin 75176-06-6 98%
    [D-Trp8,Tyr11] Somatostatin is an analogue of somatostatin. Somatostatin is a hormone that regulates a variety of bodily functions. DTrp8 residue can increase stability.
    [D-Trp8,Tyr11] Somatostatin
  • HY-P3946
    Prolactin-Releasing Peptide (1-31), bovine 98%
    Prolactin-Releasing Peptide (1-31), bovine is a fragment of the prolactin releasing peptide (PrRP).
    Prolactin-Releasing Peptide (1-31), bovine
  • HY-P3959
    (Tyr0)-Urocortin, rat 187111-93-9 98%
    (Tyr0)-Urocortin, rat is a high-affinity agonist of corticotropin-releasing factor receptor type 1 (CRF-R1) and type 2 (CRF-R2). (Tyr0)-Urocortin, rat shows inhibitory binding constants (Ki) of 1-2 nM.
    (Tyr0)-Urocortin, rat
  • HY-P3962
    [Phe2]-TRH 34783-35-2 98%
    [Phe2]-TRH is a thyrotropin releasing hormone analogue, equipping a conformational similarity with Leu5-enkephalin.
    [Phe2]-TRH
  • HY-P3964
    TRH Precursor Peptide 128578-17-6 98%
    TRH Precursor Peptide is a precursor peptide of thyrotropin-releasing hormone (TRH). TRH Precursor Peptide formation of TRH in rat brain and pituitary is zinc-dependent.
    TRH Precursor Peptide
  • HY-P3969
    Prepro-TRH-(160-169) 122018-91-1 98%
    Prepro-TRH-(160-169) is one of the connecting peptides of thyrotropin-releasing hormone prohormone (pro-TRH), potentiates TRH-induced thyrotropin (TSH) release.
    Prepro-TRH-(160-169)
  • HY-P3975
    Glp-His-Pro-Gly-NH2 41880-59-5 98%
    Glp-His-Pro-Gly-NH2 (pGlu-His-Pro-Gly-NH2) is a peptide containing 4 amino acids. Glp-His-Pro-Gly-NH2 stimulates gonadotrophin, luteinizing hormone (LH) and follicle stimulating hormone (FSH) release.
    Glp-His-Pro-Gly-NH2
  • HY-P4007
    [Pmp1,DTyr(OEt)2,Val4,Cit8] Vasopressin 1426174-49-3 98%
    [Pmp1,DTyr(OEt)2,Val4,Cit8] Vasopressin is an analogue of Vasopressin.
    [Pmp1,DTyr(OEt)2,Val4,Cit8] Vasopressin
  • HY-P4008
    [Deamino-4-valine, 8-D-arginine]-Vasopressin 43157-23-9 98%
    [Deamino-4-valine, 8-D-arginine]-Vasopressin (dVDAVP) is a highly potent and specific antidiuretic agent possessing protracted effects.
    [Deamino-4-valine, 8-D-arginine]-Vasopressin
  • HY-P4012
    [Asu1,6-Arg8]Vasopressin 40944-53-4 98%
    [Asu1,6-Arg8]Vasopressin is an vasopressin agonist which potentiates cyclic AMP accumulation and ACTH release induced by corticotropin-releasing factor (CRF) in rat anterior pituitary cells in culture.
    [Asu1,6-Arg8]Vasopressin
  • HY-P4249
    Gly-Gly-Arg 54944-27-3 98%
    Gly-Gly-Arg is a tripeptide, and a “pumping pheromone” released from the hatching eggs. Gly-Gly-Arg induces pleopod pumping activity, with the threshold concentration of 10 nM. Gly-Gly-Arg shows maximum percentage response of 58.3%. Gly-Gly-Arg act as pheromones and controlls larval release in subtidal crustaceans.
    Gly-Gly-Arg
  • HY-P4290
    Antiulcer Agent 2 111543-77-2 98%
    Antiulcer Agent 2 is a tetrapeptide containing aspartic acid, alanine, histidine, and lysine. Antiulcer Agent 2 is present at the N-terminal of human albumin. Antiulcer Agent 2 has potential applications in ulcers and active oxygen generation.
    Antiulcer Agent 2
  • HY-P4397
    (d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin 115499-13-3 98%
    (d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin, an oxytocin receptor antagonist, abolishes oxytocin-enhanced inhibitory postsynaptic currents in CA1 pyramidal neurons.
    (d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin
  • HY-P4413
    (Des-Glu5)-ACTH (1-24) (human, bovine, rat) 1815617-95-8 98%
    (Des-Glu5)-ACTH (1-24) (human, bovine, rat) is an analogue of Adrenocorticotropic hormone (ACTH; HY-106373). ACTH is a polypeptide tropic hormone produced by the anterior pituitary gland, regulating cortisol and androgen production.
    (Des-Glu5)-ACTH (1-24) (human, bovine, rat)
  • HY-P4432
    (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon) 88848-87-7 98%
    (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon) is a GnRH analog that induces ovulation and/or spawning in farmed fish.
    (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon)
  • HY-P4456
    (Des-His6)-ACTH (1-24) (human, bovine, rat) 1926163-11-2 98%
    (Des-His6)-ACTH (1-24) (human, bovine, rat) is an analogue of Adrenocorticotropic hormone (ACTH; HY-106373). ACTH is a polypeptide tropic hormone produced by the anterior pituitary gland, regulating cortisol and androgen production.
    (Des-His6)-ACTH (1-24) (human, bovine, rat)
  • HY-P4523
    FA-Ala-Arg 76079-06-6 98%
    FA-Ala-Arg is a dipeptide with furylacryloyl group. FA-Ala-Arg breaks down to produce arginine. While cell-surface Carboxypeptidase-D (CPD) also increases intracellular Arg, which is converted to nitric oxide (NO). FA-Ala-Arg enhances NO production in MCF-7 cells. FA-Ala-Arg also increases the cell survival of prolactin (PRL)-treated cells, PRL regulates CPD mRNA levels in cells.
    FA-Ala-Arg
  • HY-P4542
    (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) 150646-45-0 98%
    (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) is a CRF antagonist. (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) prevents the IL-1a induced Luteinizing hormone (LH) inhibition.
    (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat)
Cat. No. Product Name / Synonyms Application Reactivity