2. Endocrinology

Endocrinology

Endocrinology

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Found in most species of the animal kingdom, the endocrine system consists of glands that secrete hormones, and receptors that detect and react to the hormones. In response to environmental stimuli, the endocrine system secretes hormones and uses them as chemical messengers to orchestrate physiological, developmental and reproductive changes that affect the entire body for a long period of time. In order to maintain the proper functioning of the body through its entire life cycle, the endocrine system utilizes a complex feedback mechanism to fine-tune the balance of hormones in the bloodstream. Even a slight disruption to endocrine system’s function can throw off the delicate balance of hormones in the human body and lead to an endocrine disorder, or endocrine disease, such as diabetes, adrenal insufficiency, hyper- or hypothyroidism, and polycystic ovary syndrome (PCOS).

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-E70170
    Heparan Sulfate 2-O-Sulfotransferase 1
    Heparan Sulfate 2-O-Sulfotransferase 1 is a sulfotransferase and influences dermatan sulfate biosynthesis.
    Heparan Sulfate 2-O-Sulfotransferase 1
  • HY-E70171
    Heparan Sulfate 3-O-Sulfotransferase 1
    Heparan Sulfate 3-O-Sulfotransferase 1 is a sulfotransferase. Heparan Sulfate 3-O-Sulfotransferase controls cellular production of the anticoagulant heparan sulfate related structure.
    Heparan Sulfate 3-O-Sulfotransferase 1
  • HY-E70173
    Heparan Sulfate 6-O-Sulfotransferase 1
    Heparan Sulfate 6-O-Sulfotransferase 1 is a sulfotransferase. Heparan Sulfate 6-O-Sulfotransferase 1 is important in heparan sulfate biosynthesis.
    Heparan Sulfate 6-O-Sulfotransferase 1
  • HY-E70174
    Heparan Sulfate 6-O-Sulfotransferase 3 98%
    Heparan Sulfate 6-O-Sulfotransferase 3 is a sulfotransferase. Heparan Sulfate 6-O-Sulfotransferase 3 is important in heparan sulfate biosynthesis.
    Heparan Sulfate 6-O-Sulfotransferase 3
  • HY-E70175
    Heparan Sulfate Glucosamine 3-O-Sulfotransferase 3 98%
    Heparan Sulfate Glucosamine 3-O-Sulfotransferase 3 is a sulfotransferase. Heparan Sulfate Glucosamine 3-O-Sulfotransferase 3 is important in heparan sulfate biosynthesis.
    Heparan Sulfate Glucosamine 3-O-Sulfotransferase 3
  • HY-E70176
    N-Deacetylase/N-Sulfotransferase 1 98%
    N-Deacetylase/N-Sulfotransferase 1 is a sulfotransferase. N-Deacetylase/N-Sulfotransferase 1 modifies heparan sulfate-dependent growth factor and morphogen signalling.
    N-Deacetylase/N-Sulfotransferase 1
  • HY-E70177
    N-Deacetylase/N-Sulfotransferase 2 98%
    N-Deacetylase/N-Sulfotransferase 2 is a sulfotransferase. N-Deacetylase/N-Sulfotransferase 2 synthesizes serglycin-bound heparin chains in mast cells.
    N-Deacetylase/N-Sulfotransferase 2
  • HY-I0021A
    Bepotastine tosylate 1160415-45-1 98%
    Bepotastine tosylate is a selective and orally active second-generation histamine H1 receptor antagonist. Bepotastine tosylate can suppress the expression of nerve growth factor (NGF). Bepotastine tosylate can be used in studies of allergic rhinitis, allergic conjunctivitis and urticaria/pruritus.
    Bepotastine tosylate
  • HY-N0011R
    Baohuoside I (Standard) 113558-15-9
    Baohuoside I (Standard) is the analytical standard of Baohuoside I. This product is intended for research and analytical applications. Baohuoside I, a flavonoid isolated from Epimedium koreanum Nakai, acts as an inhibitor of CXCR4, downregulates CXCR4 expression, induces apoptosis and shows anti-tumor activity.
    Baohuoside I (Standard)
  • HY-N0132R
    Synephrine (Standard) 94-07-5 98%
    Synephrine (Standard) is the analytical standard of Synephrine. This product is intended for research and analytical applications. Synephrine (Oxedrine), an alkaloid, is an α-adrenergic and β-adrenergic agonist derived from the Citrus aurantium. Synephrine is a sympathomimetic compound and can be used for weight loss.
    Synephrine (Standard)
  • HY-N0755R
    Rhoifolin (Standard) 17306-46-6 98%
    Rhoifolin (Standard) is the analytical standard of Rhoifolin. This product is intended for research and analytical applications. Rhoifolin is a flavone glycoside can be isolated from Rhus succedanea. Rhoifolin has anti-diabetic effect acting through enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and glucose transporter 4 (GLUT 4) translocation. Rhoifolin has an anti-inflammatory action via multi-level regulation of inflammatory mediators. Rhoifolin ameliorates titanium particle-stimulated osteolysis and attenuates osteoclastogenesis via RANKL-induced NF-κB and MAPK pathways. Rhoifolin also has cytotoxic activity against different cancer cell lines.
    Rhoifolin (Standard)
  • HY-N0778R
    Isorhamnetin-3-O-neohespeidoside (Standard) 55033-90-4
    Isorhamnetin-3-O-neohespeidoside (Standard) is the analytical standard of Isorhamnetin-3-O-neohespeidoside (HY-N0778). This product is intended for research and analytical applications. Isorhamnetin-3-O-neohespeidoside is a flavonoid. Isorhamnetin-3-O-neohespeidoside can be isolated from Typha angustifolia. Isorhamnetin-3-O-neohespeidoside inhibits xanthine oxidase activity with an IC50 of 48.75 μg mL. Isorhamnetin-3-O-neohespeidoside has antioxidant and osteoclastogenic activities. Isorhamnetin-3-O-neohespeidoside can be used in research of bone.
    Isorhamnetin-3-O-neohespeidoside (Standard)
  • HY-N0835R
    (20S)-Protopanaxatriol (Standard) 34080-08-5 98%
    (20S)-Protopanaxatriol (Standard) is the analytical standard of (20S)-Protopanaxatriol. This product is intended for research and analytical applications. (20S)-Protopanaxatriol is a metabolite of ginsenoside. (20S)-Protopanaxatriol works through the glucocorticoid receptor (GR) and estrogen receptor (ER), and is also a LXRα inhibitor. (20S)-Protopanaxatriol shows a broad spectrum of antitumor effects.
    (20S)-Protopanaxatriol (Standard)
  • HY-N0908R
    Ginsenoside Rg5 (Standard) 186763-78-0
    Ginsenoside Rg5 (Standard) is the analytical standard of Ginsenoside Rg5. This product is intended for research and analytical applications. Ginsenoside Rg5 is the main component of Red ginseng and IGF-1R agonist. Ginsenoside Rg5 compets for the binding site of IGF-1R and blocks the binding of IGF-1 to IGF-1R (IC50 about 90 nM). Ginsenoside Rg5 also inhibits the mRNA expression of COX-2 via suppression of the DNA binding activities of NF-κB p65.
    Ginsenoside Rg5 (Standard)
  • HY-N10226
    Thielavin B 71950-67-9 98%
    Thielavin B is an inhibitor of prostaglandin biosynthesis produced by Thielavia terricola. Thielavin B effectively influences the prostaglandin E2 synthesis from the endoperoxide. Thielavin B is significantly effective on carrageenan-induced oedema of rats when administered intravenously.
    Thielavin B
  • HY-N10763
    N-Methylcorydaldine 6514-05-2 98%
    N-Methylcorydaldine, an alkaloid, shows promising anti-secretory activity.
    N-Methylcorydaldine
  • HY-N12638
    Endolide F 98%
    Endolide F (Compound 2) is a proline-containing lactone. Endolide F is a moderate antagonist of the arginine antidiuretic hormone V1A receptor.
    Endolide F
  • HY-N12867
    Amarasterone A 20853-88-7 98%
    Amarasterone A (22) is an ecdysteroid that can be isolated from Rhaponticum carthamoides.
    Amarasterone A
  • HY-N12999
    Stigmast-5-en-3-ol 5779-62-4
    Stigmast-5-en-3-ol induces cancer cell apoptosis and inhibits proliferation by increasing the production of Bax, Caspase-9, p53, and PARP cleavage and reducing Bcl-xl expression. Stigmast-5-en-3-ol exhibits potent inhibitory activity against glucoamylase and α-amylase and possesses high antioxidant activity. Stigmast-5-en-3-ol can be used in the research of diseases such as leukemia, breast cancer, type 2 diabetes, and obesity.
    Stigmast-5-en-3-ol
  • HY-N13127
    Segetalin C 164991-90-6 98%
    Segetalin C is a cyclic peptide that increases uterine weight in ovariectomized rats (2.5 mg/kg).
    Segetalin C
Cat. No. Product Name / Synonyms Application Reactivity