2. Endocrinology

Endocrinology

Endocrinology

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Found in most species of the animal kingdom, the endocrine system consists of glands that secrete hormones, and receptors that detect and react to the hormones. In response to environmental stimuli, the endocrine system secretes hormones and uses them as chemical messengers to orchestrate physiological, developmental and reproductive changes that affect the entire body for a long period of time. In order to maintain the proper functioning of the body through its entire life cycle, the endocrine system utilizes a complex feedback mechanism to fine-tune the balance of hormones in the bloodstream. Even a slight disruption to endocrine system’s function can throw off the delicate balance of hormones in the human body and lead to an endocrine disorder, or endocrine disease, such as diabetes, adrenal insufficiency, hyper- or hypothyroidism, and polycystic ovary syndrome (PCOS).

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N12937
    (Z)-7-Decenyl acetate 13857-03-9 98%
    (Z)-7-Decenyl acetate is a synthetic insect sex pheromone used for attracting turnip moths (Agrotis segetum), which can be isolated from analogs with lower activity than natural pheromones.
    (Z)-7-Decenyl acetate
  • HY-N12938
    (Z)-7-Hexadecenyl acetate 23192-42-9 98%
    (Z)-7-Hexadecenyl acetate is a pheromone used for capturing male tobacco budworm moths (Heliothis virescens), which can be isolated from the brush glands or hair pencils on the abdomen or hind wings of insects.
    (Z)-7-Hexadecenyl acetate
  • HY-N12939
    (11Z,13Z)-Hexadecadien-1-ol 71720-83-7 98%
    (11Z,13Z)-Hexadecadien-1-ol is an insect sex pheromone attractive to male navel orangeworm moths (Amyeloistransitella), a secretion of the moth Z11, which can be isolated from Z13-16:Ald analogs.
    (11Z,13Z)-Hexadecadien-1-ol
  • HY-N13076
    Neo-sagittasine A 1804014-67-2 98%
    Neo-sagittasine A (compound 2) is an estrogen biosynthesis promoter that can enhance estrogen biosynthesis in human ovarian granulosa-like KGN cells. Neo-sagittasine A can be isolated from Epimedium brevifolium.
    Neo-sagittasine A
  • HY-N13220
    Soybean Extract 98%
    Soybean Extract is a soybean extract, and its components include: Isoflavone. Soybean Extract has an increased content of isoflavone aglycones after biotransformation, which is an estrogen-like bioactive compound with effective type I collagen enhancement..
    Soybean Extract
  • HY-N13290
    10-Chloroestra-1,4-diene-3,17-dione 91413-55-7 98%
    10-Chloroestra-1,4-diene-3,17-dione (10-CIEsra) is a derivative of estrogen receptor.
    10-Chloroestra-1,4-diene-3,17-dione
  • HY-N14632
    Louisianin A 171784-03-5 98%
    Louisianin A is a non-steroidal growth inhibitor of testosterone-responsive SC 115 cells.
    Louisianin A
  • HY-N14633
    Louisianin B 1192169-18-8 98%
    Louisianin B is a non-steroidal growth inhibitor of testosterone-responsive SC 115 cells.
    Louisianin B
  • HY-N14634
    Louisianin C 171784-05-7 98%
    Louisianin C is a non-steroidal growth inhibitor of testosterone-responsive SC 115 cells.
    Louisianin C
  • HY-N1508R
    Ecliptasaponin A (Standard) 78285-90-2
    Ecliptasaponin A (Standard) is the analytical standard for Ecliptasaponin A (HY-N1508). Ecliptasaponin A is an orally active pentacyclic triterpenoid saponin. Ecliptasaponin A exerts anti-tumor activity by activating ASK1/JNK pathway, inducing apoptosis and autophagy in lung cancer cells. Ecliptasaponin A exerts anti-inflammatory/anti-fibrotic effects and protects the cardiovascular system by inhibiting the HMGB1/TLR4/NF-κB pathway, and the expression of COX-2 and MMP-9. Ecliptasaponin A can enhance SOD activity, reduce MDA levels, and alleviate oxidative stress damage. Ecliptasaponin A exerts chondroprotective effects by inhibiting the expression of MMP13 and regulating inflammatory factors. Ecliptasaponin A improves ovarian function and regulates sex hormones by upregulating the expression of ESR1 receptors.
    Ecliptasaponin A (Standard)
  • HY-N15336
    Tschimganin 38970-49-9 98%
    Tschimganin is an ester of terpenoid acids with estrogen activity, which is found in F. tschimganica. Tschimganin can increase the growth of uterus of immature rats.
    Tschimganin
  • HY-N15342
    Tschimganidin 39380-16-0 98%
    Tschimganidin is an ERα agonist with an IC50 of 1.4 μM. Found in plants of the Apiaceae family, Tschimganidin is a terpenoid compound with anti-obesity activity. It can be used for research in the field of endocrine and metabolic disorders.
    Tschimganidin
  • HY-N15362
    5α-Pregnane-3β,17α,20α-triol 570-50-3 98%
    5α-Pregnane-3β,17α,20α-triol is an endogenous steroid compound. 5α-Pregnane-3β,17α,20α-triol is the metabolite of Pregnenolone (HY-B0151) or Progesterone (HY-N0437). 5α-Pregnane-3β,17α,20α-triol is promising for research of the endocrine function of the placenta and the mechanisms related to steroid hormone metabolism during pregnancy.
    5α-Pregnane-3β,17α,20α-triol
  • HY-N15363
    5-Pregnene-3β,17a,20a-triol 85202-13-7 98%
    5-Pregnene-3β,17a,20a-triol is an endogenous steroid compound. 5-Pregnene-3β,17a,20a-triol plays a role in maintaining the body's hormonal balance. 5-Pregnene-3β,17a,20a-triol is promising for research of congenital steroid synthesis enzyme deficiency diseases.
    5-Pregnene-3β,17a,20a-triol
  • HY-N15576
    Lasiol 131479-19-1 98%
    Lasiol is a novel acyclic monoterpene alcohol that can be found in the mandibular gland secretions of the ant Lasius meridionalis. Lasiol has sex pheromone function and can be used in sex pheromone research.
    Lasiol
  • HY-N1570R
    Pterosin B (Standard) 34175-96-7
    Pterosin B (Standard) is the analytical standard of Pterosin B (HY-N1570). This product is intended for research and analytical applications. Pterosin B is an indanone. Pterosin B can be obtained from Pteridium aquilinum. Pterosin B is a Sik3 signaling inhibitor. Pterosin B inhibits Klf5 expression and reduces β-amyloid deposition. Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice. Pterosin B inhibits cardiomyocyte hypertrophy, improves cognitive impairment, and lowers blood glucose. Pterosin B can be used in research on arthritis, Alzheimer's disease, pathological cardiac hypertrophy and diabetes.
    Pterosin B (Standard)
  • HY-N1581R
    Quassin (Standard) 76-78-8
    Quassin (Standard) is the analytical standard of Quassin. This product is intended for research and analytical applications. Quassin (Nigakilactone D) is a bioactive triterpenoid from stem bark extract of Quassia amara. Quassin inhibits P. falciparum with an IC50 of 0.15 μM. Quassin possesses reversible antifertility, anti-estrogenic and anti-plasmodial activity.
    Quassin (Standard)
  • HY-N16435
    Plumericin 77-16-7 98%
    Plumericin is an anti-inflammatory, antioxidant, and antibacterial agent. Plumericin reduces Apoptosis, promotes Nrf-2 and inhibits NF-κB and AhR activation, blocks STAT3 signaling. Plumericin inhibits Mycobacterium tuberculosis growth. Plumericin can be used for the research of chronic kidney disease, vascular diseases, inflammatory bowel diseases, peritonitis, and tuberculosis.
    Plumericin
  • HY-N18905
    α-D-Glucosyl hesperidin 161713-86-6 98%
    α-D-Glucosyl hesperidin is an orally effective structural modification derivative of Hesperidin (HY-15337) with anti-apoptotic (apoptosis) and antioxidant activities. α-D-Glucosyl hesperidin upregulates the expression of the Bcl-2 gene, while downregulating the expressions of the Bax and caspase-3 genes. α-D-Glucosyl hesperidin increases total antioxidant capacity, SOD and catalase levels, and decreases malondialdehyde and glutathione levels. α-D-Glucosyl hesperidin improves sperm motility, viability and plasma membrane function, while restoring reproductive organ weight and seminiferous tubule structure. α-D-Glucosyl hesperidin increases fertility index and exerts a synergistic protective effect with Proanthocyanidins (HY-N0794) in male rats with testicular ischemia-reperfusion injury. α-D-Glucosyl hesperidin can be used in the research of testicular ischemia-reperfusion injury.
    α-D-Glucosyl hesperidin
  • HY-N1919R
    Ajmalicine (Standard) 483-04-5
    Ajmalicine (Standard) is the analytical standard of Ajmalicine. This product is intended for research and analytical applications. Ajmalicine (Raubasine) is a potent adrenolytic agent which preferentially blocks α1-adrenoceptor. Ajmalicine is an reversible but non-competitive nicotine receptor full inhibitor, with an IC50 of 72.3 μM. Ajmalicine also can be used as anti-hypertensive, and serpentine, with sedative activity.
    Ajmalicine (Standard)
Cat. No. Product Name / Synonyms Application Reactivity