2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P2251
    T-peptide 2022956-62-1 98%
    T-peptide, a Tuftsin analog, can be used for the research of human immunodeficiency virus (HIV) infection. T-peptide prevents cellular immunosuppression and improves survival rate in septic mice. T-peptide also can inhibit the growth of residual tumor cells after surgical resection.
    T-peptide
  • HY-P2289
    β-defesin 1 (pig) 98%
    β-defesin 1 (pig) (pBD-1) is an endogenous and constitutively expressed antimicrobial peptide (AMP) from porcine tissues, particularly expresses in pig mucosal epithelial sites. β-defesin 1 (pig) has antimicrobial activities and contributes to mucosal and systemic host defenses in pigs.
    β-defesin 1 (pig)
  • HY-P2302
    Defensin HNP-3 human 136661-76-2 98%
    Defensin HNP-3 human is an α-defensin stored in the azurophilic granules of human neutrophils. Defensin HNP-3 human exerts broad-spectrum bactericidal, antifungal and antiviral activities mainly by forming bacterial membrane pores, and acts as a chemoattractant for monocytes and T cells. Defensin HNP-3 human maintains epithelial integrity to support periodontal tissue homeostasis, and exerts concentration-dependent effects on epithelial cell proliferation, adhesion and bacterial adhesion. Defensin HNP-3 human targets solid tumors and leukemia by inducing single-strand DNA breaks and membrane permeabilization in tumor cells via electrostatic binding and pore formation. Defensin HNP-3 human is abundant in human tongue squamous cell carcinoma and neutrophils infiltrating oral squamous cell carcinoma. Defensin HNP-3 human can be applied to research related to periodontitis and human tongue squamous cell carcinoma.
    Defensin HNP-3 human
  • HY-P2313
    Human β-defensin-2 372146-20-8 98%
    Human β-defensin-2 (HβD-2) is a small cysteine-rich cationic skin-antimicrobial peptide (SAP) produced by a number of epithelial cells.Human β-defensin-2 has antimicrobial activity against gram-negative bacteria and Candida, but not gram-positive Staphylococcus aureus. Human β-defensin-2 can be used for the study of colitis.
    Human β-defensin-2
  • HY-P2318
    Bac2A TFA 231306-42-6 98%
    Bac2A TFA is an antimicrobial and immunomodulatory peptide. Bac2A TFA is a linear variant of bactenecin and is very effective against fungal pathogens.
    Bac2A TFA
  • HY-P2328
    Gramicidin C 9062-61-7 98%
    Gramicidin C is a naturally occuring polypeptide antibiotic isolated from B. brevis var. G.B.
    Gramicidin C
  • HY-P2331
    Actagardin 59165-34-3 98%
    Actagardin is a tetracyclic lantibiotic produced by several species of Actinoplanes. It is composed of macrocyclic rings formed by thioether bridges. Actagardin preferably targets Gram-positive bacteria, inhibiting the synthesis of peptidoglycan.
    Actagardin
  • HY-P2344
    HIV Protease Substrate 1 223769-59-3 98%
    HIV Protease Substrate 1, a fiuorogenic HIV protease substrate, can be used to study enzymatic activity of HIV protease.
    HIV Protease Substrate 1
  • HY-P2363
    Leucinostatin K 109539-57-3 98%
    Leucinostatin K is a peptide antibiotic with anti-gram-positive bacterial and fungal effects, which is found in Paecilomyces lilacinus.
    Leucinostatin K
  • HY-P2365
    Histatin-8 127637-03-0 98%
    Histatin-8 is a part of the Histatin-3 central sequence and is known as hemagglutination-inhibiting peptide. Histatin-8 is a potent anti-fungal peptide. Histatin-8 shows antimicrobial activity against yeast strains. Histatin-8 can be used for oral thrush research.
    Histatin-8
  • HY-P2379
    His-Cys-Lys-Phe-Trp-Trp 172546-75-7 98%
    His-Cys-Lys-Phe-Trp-Trp is an inhibitor for the human immunodeficiency virus (HIV) integrase with an IC50 of 2 μM.
    His-Cys-Lys-Phe-Trp-Trp
  • HY-P2450
    Leucinostatin A 76600-38-9 98%
    Leucinostatin A (Antibiotic P168) is a nonapeptide exerting a remarkable activity especially against Candida albicans and Cryptococcus neoformans. Leucinostatin A is a hydrophobic nonapeptide antibiotic. Leucinostatin A inhibits prostate cancer growth through reduction of insulin-like growth factor-I expression in prostate stromal cells. Antiprotozoal activies.
    Leucinostatin A
  • HY-P2457
    rCRAMP (rat) 376364-38-4 98%
    rCRAMP (rat) is the rat cathelin-related antimicrobial peptide. rCRAMP (rat) contributes to the antibacterial activity in rat brain peptide/protein extracts. rCRAMP (rat) is a potential key player in the innate immune system of rat CNS.
    rCRAMP (rat)
  • HY-P2458
    CAP18 (rabbit) 152742-15-9 98%
    CAP18 (rabbit) is a 37 amino acids antimicrobial peptide originally isolated from rabbit granulocytes. CAP18 (rabbit) has broad antimicrobial activity against both Gram-positive (IC50, 130-200 nM) and Gram-negative (IC50, 20-100 nM) bacteria. CAP18 (rabbit) has the potential for bacterial sepsis research.
    CAP18 (rabbit)
  • HY-P2483
    Octaarginine 148796-86-5 98%
    Octaarginine is a cell-penetrating peptide and proteasome inhibitor. Octaarginine exhibits mixed-type inhibition against 20S proteasome chymotrypsin-like, caspase-like, and trypsin-like activities, and inhibits 26S proteasome activity with decreased efficiency. Octaarginine induces ubiquitin-conjugated protein accumulation, mediates HSPG-dependent cellular internalization via macropinocytosis, enhances liposomal cargo uptake and gene delivery. Octaarginine can be used for the research of cervix carcinoma, collagen antibody-induced arthritis, and bacterial infections.
    Octaarginine
  • HY-P2561
    Influenza Matrix Protein (61-72) 1286245-45-1 98%
    Influenza Matrix Protein (61-72) is a peptide fragment derived from matrix protein of influenza viruses, corresponds to amino acids 61-72. Influenza Matrix Protein (61-72) is a specific epitope which can induce CD4+ T-cell response.
    Influenza Matrix Protein (61-72)
  • HY-P2599
    A83586C 116364-81-9 98%
    A83586C is a new type of peptide antibiotic that is effective against Gram-positive bacteria.
    A83586C
  • HY-P2656
    β-Defensin-4 (human) 370570-43-7 98%
    β-Defensin-4 human is an inducible peptide with a specific salt-sensitive spectrum of antimicrobial activity.
    β-Defensin-4 (human)
  • HY-P2763
    beta-Glucanase 9074-98-0 98%
    beta-Glucanase belongs to glycosyl hydrolase family that hydrolyzes β-glucan polysaccharide, producing 3-O-cellotriosyl-d-glucose and 3-O-cellobiosyl-d-glucose. beta-Glucanase is capable of protecting plants against different fungal pathogens.
    beta-Glucanase
  • HY-P3070
    H2-D b restricted epitopes VSV Nucleoprotein (52-59) 132326-74-0 98%
    H2-D b restricted epitopes VSV Nucleoprotein (52-59) is a 9-mer peptide derived from the nucleoprotein of Vesicular Stomatitis Virus (VSV). H2-D b restricted epitopes VSV Nucleoprotein (52-59) binds to MHC class I molecules and presents itself to CD8+ T cells, thereby activating cytotoxic T lymphocytes (CTLs), which can recognize and kill cells expressing the corresponding antigen. H2-D b restricted epitopes VSV Nucleoprotein (52-59) can be used in the development of CTL vaccines against Ebola virus.
    H2-D b restricted epitopes VSV Nucleoprotein (52-59)
Cat. No. Product Name / Synonyms Application Reactivity