1. Cell Cycle/DNA Damage
    Cytoskeleton
  2. Microtubule/Tubulin
  3. T-peptide

T-peptide 

Cat. No.: HY-P2251
Handling Instructions

T-peptide is a peptide derived from microtubule binding repeat of Tau protein. T-peptide self-assembles into 30-55 nm paired helical filaments (PHFs) even in the absense of inducers. T-peptide is cytotoxic in multiple cell lines including cortical neurons, cerebellar granular neurons, neuroblastoma cells, kidney fibroblasts and HEK293 cells. T-peptide co-localizes with pathological hyperphosphorylated forms of tau in vitro.

For research use only. We do not sell to patients.

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T-peptide Chemical Structure

T-peptide Chemical Structure

CAS No. : 2022956-62-1

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Description

T-peptide is a peptide derived from microtubule binding repeat of Tau protein. T-peptide self-assembles into 30-55 nm paired helical filaments (PHFs) even in the absense of inducers. T-peptide is cytotoxic in multiple cell lines including cortical neurons, cerebellar granular neurons, neuroblastoma cells, kidney fibroblasts and HEK293 cells. T-peptide co-localizes with pathological hyperphosphorylated forms of tau in vitro.

Molecular Weight

2195.66

Formula

C₉₂H₁₇₁N₄₅O₁₈

CAS No.

2022956-62-1

Sequence

Ac-{Val}{Gln}{Ile}{Val}{Tyr}{Lys}{Arg}{Arg}{Arg}{Arg}{Arg}{Arg}{Arg}{Arg}{Arg}-NH2

Sequence Shortening

Ac-VQIVYKRRRRRRRRR-NH2

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Keywords:

T-peptideMicrotubule/TubulinInhibitorinhibitorinhibit

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T-peptide
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